Jalyn (Dutasteride/Tamsulosin)

Do’s

• If available from your pharmacist, read the Patient Information Leaflet before you start taking Jalyn and each time you get a refill. If you have any questions, ask your healthcare provider.
• Take this medication by mouth as directed by your healthcare provider, typically once daily, 30 minutes after the same meal each day. Swallow the medication whole.
• Take this medication regularly to derive the greatest benefit from it. Establish a routine by taking it at the same time each day to aid in remembering.
• It may take up to 4 weeks to observe an improvement in symptoms. If your symptoms do not improve after 4 weeks or if they worsen, inform your healthcare provider.

Don’ts

• Refrain from crushing, chewing, or opening the capsules.
• This medication may lead to a sudden drop in blood pressure, potentially causing dizziness or fainting. The risk is higher when initiating this drug or when restarting treatment after a prior cessation. During these times, avoid circumstances where you may be at risk of injury if you experience fainting.
• Due to the potential for this drug to be absorbed through the skin and harm an unborn baby, women who are pregnant or may become pregnant should refrain from handling this medication.

Common Side Effects:

• Decreased libido (sex drive)
• Decreased amount of semen released during sex
• Impotence (trouble getting or keeping an erection)
• Breast tenderness or enlargement
• Dizziness
• Enlarged or painful breasts
• Runny nose
• Decreased blood pressure
• Ejaculation problems

Serious Side Effects:

• Allergic reactions: swelling of the face, tongue, or throat, difficulty breathing
• Severe skin reaction: fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling
• Painful or prolonged penis erection

Consult a healthcare provider for medical advice about side effects, as this is not a complete list and others may occur. 

Jalyn may interact with other medications, affecting their effectiveness or causing increased side effects. Consult a healthcare provider before taking any drug, changing any diet, or commencing or discontinuing any course of treatment.

Patients starting treatment with Jalyn should be cautious to avoid situations where injury could result should syncope occur, such as driving, operating machinery, or performing hazardous tasks. Patients should be advised to sit or lie down at the first signs of orthostatic hypotension.

Jalyn reduces serum PSA levels, and increases in PSA levels while on treatment may signal the presence of prostate cancer and should be evaluated by a healthcare provider.

There was an increase in high-grade prostate cancer in men treated with 5-alpha-reductase inhibitors, including dutasteride (a component of Jalyn), compared with those treated with placebo.

Jalyn is contraindicated for use in pregnancy, and dutasteride use is contraindicated in females who are pregnant.

The information provided here is not exhaustive. Consult a healthcare provider for personalized guidance.

Product Insert {https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/022460s011lbl.pdf}