Motilium (Domperidone)


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FormulationFormulation: Tablet
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$70.00 ($0.70 per tablet)

$130.00 ($0.65 per tablet)


(Generic Alternative)

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This generic medication is not available at the moment.

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Motilium (Domperidone) is used to alleviate feelings of nausea and to prevent vomiting, which may be caused by various factors such as chemotherapy, general anaesthetics, migraine, or certain medications for conditions like Parkinson's disease.

Domperidone blocks the transmission of messages between the digestive system and the brain, reducing the likelihood of nausea and vomiting. It accomplishes this by causing the muscles at the entrance of the stomach to tighten and the muscles at the exit of the stomach to relax. Additionally, it blocks messages in the brain that contribute to the sensation of sickness.

Domperidone aids in increasing milk supply by stimulating the release of prolactin, a hormone that is responsible for stimulating breast milk production.


  • Take it as prescribed by your healthcare provider: This includes following the recommended dosage and frequency. Don't take more than prescribed.
  • Take it before meals: Take Motilium 10-30 minutes before meals for maximum effectiveness in relieving indigestion and nausea.
  • Swallow whole with water: Don't crush, chew, or break the tablet.
  • Read food labels: If your indigestion is caused by certain foods, avoid them while using Motilium.
  • Stay hydrated: Drink plenty of fluids to prevent dehydration, especially if you're experiencing nausea or vomiting.


  • Don't take it for more than 4 weeks without consulting your healthcare provider: Motilium is typically meant for short-term relief.
  • Don't take it if you're pregnant or breastfeeding: Discuss alternative options with your healthcare provider if you're pregnant or breastfeeding.
  • Don't take it if you have stomach bleeding or a perforated ulcer: Motilium may worsen these conditions.
  • Don't take it with other medications without consulting your healthcare provider: Motilium can interact with certain medications.
  • Don't use it as a substitute for a healthy diet and lifestyle changes: Motilium is meant to provide temporary relief, not a long-term solution. If you experience frequent indigestion, address the underlying cause through dietary adjustments or lifestyle changes.

Common side effects of Motilium (domperidone) may include:

  • Dry mouth
  • Headache
  • Nervousness
  • Depression
  • Dizziness
  • Tiredness
  • Irritability
  • Sleepiness or drowsiness
  • Fits or seizures
  • Agitation
  • Regurgitation
  • Diarrhea
  • Constipation
  • Nausea
  • Changes in appetite
  • Heartburn
  • Rash or itchy skin
  • Itchy eyes and crusty eyelids with discharge
  • Mouth ulcers or cold sores
  • Lowering of sexual drive (libido) in men

Serious side effects that may require immediate medical attention include:

  • Swelling of the hands, feet, ankles, face, lips, or throat causing difficulty in swallowing or breathing, along with an itchy, lumpy rash (hives) or nettle rash (urticaria), indicating an allergic reaction
  • Uncontrolled movements, including irregular eye movements, unusual movements of the tongue, and abnormal posture such as a twisted neck, trembling, and muscle stiffness
  • Very fast or unusual heartbeat, which could be a sign of a life-threatening heart problem
  • Seizures

This is not an exhaustive list, and other side effects may occur. If you experience any unusual or severe side effects while taking Motilium,  contact your healthcare provider for medical advice.

Movicol is not recommended for children below the age of 2 years old. Their digestive systems are still developing and may react differently to the medication.

Drink plenty of fluids while taking Movicol to avoid dehydration. As Movicol works by drawing water into the stool, proper hydration ensures your body has enough fluids to function normally.

Consult your healthcare provider before using Movicol if you have certain medical conditions like heart problems, severe kidney disease, or bowel obstruction. Movicol may not be suitable in these cases.

Inform your healthcare provider about all medications you're taking, including prescription and over-the-counter drugs, before using Movicol. Some medications may interact with Movicol and affect its effectiveness.

In rare cases, long-term use of Movicol might lead to electrolyte imbalances, particularly low potassium levels. Your healthcare provider may monitor your electrolytes if you're using Movicol for an extended period.

While uncommon, allergic reactions to Movicol ingredients are possible. If you experience symptoms like rash, itching, or wheezing after taking Movicol, discontinue use and consult your healthcare provider immediately.

Generic name:




Strength(s): 10mg
Quantities Available: 100, 200
Important Information
The information above for Motilium (Domperidone) was provided to by third parties. In no way should this information substitute for the advice of a physician. Consult a doctor or qualified health care professional if you have any medical concerns. widget logo
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