Anugesic HC Suppository (Hydrocortisone Acetate/Pramoxine HCL/Zinc Sulfate)

Anugesic HC Suppository

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Hydrocortisone Acetate/Pramoxine HCL/Zinc Sulfate

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FormulationFormulation: Suppository
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Anugesic HC is a medication that comes in the form of a suppository. It is primarily used for the treatment of hemorrhoids and other inflammatory conditions in and around the rectum. The suppository is inserted into the rectum to provide relief from symptoms such as itching, burning, and swelling associated with these conditions.

Anugesic HC contains three active ingredients: pramoxine HCl, hydrocortisone acetate, and zinc sulfate monohydrate. It works through the combined action of its active ingredients: 

Pramoxine is a local anesthetic which works by temporarily numbing the nerves in the skin, reducing the sensation of itching and pain. 

Hydrocortisone helps to reduce inflammation, redness, and swelling in the rectal area. Whereas, Zinc sulfate helps to shrink and constrict blood vessels. This can help reduce swelling and promote healing in the affected area.


  • Use Anugesic-HC suppositories exactly as prescribed by your healthcare provider, typically once or twice daily in the morning and evening, and after each bowel movement.
  • Before insertion, wash and dry the anal area thoroughly with mild soap and water. Pat the area dry with a soft towel.
  • Lie on your side with your knees flexed towards your chest or kneel with your head on your forearms. Gently push the suppository past the anal sphincter (opening) with your finger.
  • Wash your hands thoroughly with soap and water after inserting the suppository.


  • Don't use Anugesic-HC suppositories more often than directed by your healthcare provider.
  • Don't use Anugesic-HC suppositories for longer than prescribed by your healthcare provider, typically no more than a week.
  • Don't  force insertion. If the suppository is too hard to insert, don't force it. Let it soften slightly in your hands or run it under warm water for a few seconds.
  • Don't use leftover Anugesic-HC suppositories for future hemorrhoid problems unless specifically instructed by your healthcare provider.
  • Don't  ignore worsening symptoms. If your hemorrhoid symptoms worsen or don't improve within a few days of using Anugesic-HC suppositories, consult your healthcare provider.

Common side effects:

  • Burning or stinging sensation at the application site
  • Itching or irritation at the application site
  • Mild rectal bleeding or spotting
  • Mild abdominal discomfort or cramping

Serious side effects (rare, but may require medical attention):

  • Severe rectal pain or burning
  • Bleeding from the rectum
  • Allergic reaction (rash, hives, difficulty breathing, swelling of the face, lips, tongue, or throat)

This is not an exhaustive list, and other side effects may occur. If you experience any unusual or severe side effects while taking Anugesic hc suppository, contact your healthcare provider for medical advice.

Do not use Anugesic-HC suppositories if you have:

  • Known allergy to any ingredients in the suppository, including hydrocortisone acetate (corticosteroid), zinc oxide, bismuth subgallate, or any inactive ingredients.
  • Tuberculosis or other untreated infections in the anal or rectal area.

Talk to your healthcare provider before using Anugesic-HC suppositories if you have any of the following:

  • Diabetes: Corticosteroids like hydrocortisone can increase blood sugar levels.
  • Glaucoma: Corticosteroids can worsen glaucoma.
  • Weakened immune system: You may be more susceptible to infections while using Anugesic-HC.

Inform your healthcare provider if you experience any rectal bleeding while using the suppositories.

Prolonged use of corticosteroids, especially in high doses, can cause thinning of the skin, stretch marks, or changes in skin color around the rectum.

Anugesic-HC is for rectal use only. Do not swallow the suppository.

Follow your healthcare provider's instructions for dosage and duration of treatment. Do not use the suppositories for longer than recommended.

Inform your healthcare provider of all medications you are taking, including prescription drugs, over-the-counter medications, vitamins, and herbal products. Some medications may interact with Anugesic-HC.

Discuss the risks and benefits of using Anugesic-HC with your healthcare provider if you are pregnant or breastfeeding.

Keep the medication out of reach of children.


Brand Name:

Anugesic HC Suppository

Generic name:

Hydrocortisone Acetate/Pramoxine HCL/Zinc Sulfate

Other Names:

Proctodan HC Supp

Strength(s): 10mg/20mg/10mg
Quantities Available: 12


Important Information
The information above for Anugesic HC Suppository (Hydrocortisone Acetate/Pramoxine HCL/Zinc Sulfate) was provided to by third parties. In no way should this information substitute for the advice of a physician. Consult a doctor or qualified health care professional if you have any medical concerns. widget logo
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