Nidagel (Metronidazole)

Do’s

Nidagel is typically administered intravaginally once or twice a day. The specific dosing schedule will be determined by your healthcare provider.

For once-daily dosing, Nidagel should be administered at bedtime.

Remove the cap and puncture the metal seal on the tube with the pointed tip of the cap.

Screw the end of the applicator onto the tube. Slowly squeeze the gel out of the tube and into the applicator. The plunger will stop when the applicator is full.

Unscrew the applicator and replace the cap on the tube.

Insert the filled applicator into the vagina as far as it will comfortably go. This can be done while lying on your back with your knees bent or in any comfortable position. Slowly press the plunger until it stops to deposit the gel into the vagina, and then withdraw the applicator.

If prescribed twice daily, after use, pull the plunger out of the barrel, wash both the plunger and barrel in warm soapy water, and rinse thoroughly. Gently push the plunger back into the barrel to reassemble the applicator.

If you forget to take Nidagel, apply it at your next scheduled time. 

If you think you have used too much Nidagel, contact your healthcare provider, hospital emergency department, or regional Poison Control Centre immediately, even if there are no symptoms.

Don’ts

Do not double dose.

Common Side Effects:

Vaginal discomfort/itching/discharge

Headache

Dizziness

Drowsiness

Hypotension (low blood pressure

These side effects are usually mild and may not require medical attention. However, if any of these side effects continue, worsen, or become bothersome, consult your healthcare provider.

Serious Side Effects:

Severe allergic reactions (e.g., rash, itching, swelling, severe dizziness, difficulty breathing)

Signs of a new vaginal infection, such as changes in vaginal discharge or other new vaginal symptoms

If you experience any of the serious side effects, stop using the medication and seek medical help immediately.

This is not an exhaustive list of side effects. If you have any concerns or questions about the side effects of Nidagel, consult with your healthcare provider for personalized advice.

Inform your healthcare provider about all the medications you are taking, as certain medications may interact with Nidagel. They may need to adjust the dose or take other precautions if they are taking specific medications.

Contact your healthcare provider immediately if you experience symptoms such as confusion, drowsiness, fever, a general feeling of illness, headache, loss of appetite, nausea, stiff neck or back, or vomiting. These could be symptoms of a serious condition called aseptic meningitis.

Nidagel provides minimal serum levels of metronidazole compared to oral metronidazole therapy.

Although lower serum levels are less likely to produce common reactions seen with oral metronidazole, the possibility of these and other reactions cannot be excluded.

Pregnant patients should not be treated with Nidagel during the first trimester of pregnancy. Additionally, use during menses is not recommended.

This is not an exhaustive list of warnings and precautions associated with Nidagel. If you have any concerns or questions about using Nidagel, consult with your healthcare provider for personalized advice.