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Effexor XR
(Top Brand Option)

Prescription Prescription Required
Formulation : ER Capsule
Drug Name Dosage Quantity Price Buy Now
Effexor XR 37.5mg 28 $34.00 Add To Cart
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Effexor XR 150mg 84 $212.00 Add To Cart
Effexor XR
Dosage: 37.5mg
Quantity: 28
Price: $34.00
Effexor XR
Dosage: 37.5mg
Quantity: 84
Price: $82.00
Effexor XR
Dosage: 75mg
Quantity: 28
Price: $59.00
Effexor XR
Dosage: 75mg
Quantity: 84
Price: $177.00
Effexor XR
Dosage: 150mg
Quantity: 28
Price: $77.00
Effexor XR
Dosage: 150mg
Quantity: 84
Price: $212.00

See Alternative Pricing below for savings

Buy Venlafaxine Xr

Venlafaxine Xr
(Affordable Generic Alternatives for Effexor XR)

Prescription Prescription Required
Formulation : Capsule
Drug Name Dosage Quantity Price Buy Now
Venlafaxine Xr 37.5mg 100 $68.00 Add To Cart
Venlafaxine Xr 75mg 84 $91.00 Add To Cart
Venlafaxine Xr 150mg 100 $88.00 Add To Cart
Venlafaxine Xr
Dosage: 37.5mg
Quantity: 100
Price: $68.00
Venlafaxine Xr
Dosage: 75mg
Quantity: 84
Price: $91.00
Venlafaxine Xr
Dosage: 150mg
Quantity: 100
Price: $88.00

Effexor XR Description 

Effexor XR (venlafaxine) is an antidepressant belonging to a family of medications called selective serotonin and norepinephrine reuptake inhibitors (SSNRIs). Venlafaxine influences chemicals in the brain that may be unbalanced in people with depression.

Effexor XR Uses

  • Effexor XR is a prescription antidepressant used in adults to treat a major depressive disorder, generalized anxiety disorder (GAD), social anxiety disorder (SAD), and panic disorder.

Additional information

Generic name:

Venlafaxine XR, Venlafaxine Xr


Capsule, ER Capsule


37.5mg, 75mg, 150mg

Quantities Available:

28, 84, 100

Warning & Dosage

Effexor XR Dosage 

  • The recommended initial starting dose for prolonged-release venlafaxine is 75 mg given once daily.
  • For patients not responding following the initial 75 mg, the daily dose may require dose increases up to Effexor XR dosage of 225 mg daily dose.
  • Doses can be increased at intervals of 2 weeks or greater.


  • Your physician instructed you to take Effexor XR exactly as prescribed. Pay attention to all directions on your prescription label and any medication guides or instruction sheets.
  • Follow the directions on this medication packet as your physician directs, typically once daily with food.
  • Do not take this medication by chewing, crushing, or dissolving it. Doing so can release the medicine all at once, increasing your chance of side effects. Swallow whole without crushing or chewing.


  • Effexor XR and alcohol should not be consumed together.
  • Do not take Effexor if you have uncontrolled narrow-angle glaucoma or if you are being treated with methylene blue injection.
  • Do not take Effexor XR less than 7 days before or 14 days after you have used an MAO inhibitor such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine.
  • Talk to your healthcare provider before you begin omitting Effexor XR.
  • Effexor XR is not approved for use in children; do not give this to people younger than 18 without their doctor’s advice.

Side Effects

Effexor XR Side Effects 

  • Nausea, sleepiness, dizziness, dry mouth, constipation, lack of appetite, blurred vision, nervousness, insomnia, irregular perspiration, or yawning are all possible side effects. Tell your medical practitioner immediately if any of these symptoms last or worsen.
  • Let your physician know that you expect this medication to be beneficial based on the advantages it has for you, compared to the possible side effects it may pose. Most people taking this medication will not experience any significant side effects.

Effexor XR Weight Gain: 

Many patients treated with paroxetine, mirtazapine, and other antidepressants, such as venlafaxine (EFFEXOR XR), gain a significant amount of weight.

Effexor XR side effects first week: 

Headache, nausea, diarrhea, dry mouth, and increased sweating are common reactions in the 1st week after starting cyclobenzaprine therapy. Feeling nervous, restless, fatigued, sleepy, or having trouble sleeping (insomnia) can also occur.

Effexor XR Withdrawal Symptoms 

If Effexor XR is discontinued, withdrawal symptoms may include these: 

  • Anxiety.
  • Insomnia and nightmares.
  • Fatigue.
  • Dizziness and nausea.
  • Vomiting.
  • Vertigo.
  • Mood swings and depression.
  • Flu-like symptoms.


Frequently Asked Questions 

How does Effexor XR make you feel? 

It may enhance your mood and energy level and help restore your interest in everyday activities. It may also reduce fear, anxiety, unwanted thoughts, and the number of panic attacks. Venlafaxine is an SNRI that inhibits the reuptake of serotonin and norepinephrine. 

Is Effexor XR a strong antidepressant? 

Certain SSRIs are considered effective antidepressants for all individuals, including women, says Vivien K. Burt, MD, Ph.D. One of the good things about Effexor is that it is a great option for inhibiting depression, anxiety, and anxious depression. 

Can Effexor XR cause weight gain? 

Effexor XR and Wellbutrin are less likely to cause weight gain, but Wellbutrin has a history of causing weight loss. Occasionally switching from one antidepressant to another in the same class can make a huge difference.

Should I take Effexor XR in the morning or at night? 

Your extended-release pill or capsule will work at any time as long as you take it at the same time, even through the night. If you struggle with sleep, take your tablet in the morning. 

Pricing: How much does Effexor XR cost in Canada? offers affordable pricing on this medication. We also have generic Venlafaxine XR for a much lower price. 

The information above for Effexor XR (Venlafaxine Xr) was provided to by third parties. In no way should this information substitute for the advice of a physician. Consult a doctor or qualified health care professional if you have any medical concerns.