Compazine (Prochlorperazine)

Compazine

(Brand Option)

Prescription RequiredPrescription Required
FormulationFormulation: Tablet
Select Dosage

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$49.00 ($0.49 per tablet)

Prochlorperazine

(Generic Alternative)

Prescription RequiredPrescription Required
FormulationFormulation: Tablet
Select Dosage

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$33.00 ($0.39 per tablet)

$49.00 ($0.49 per tablet)

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Compazine (prochlorperazine) is indicated for the treatment of severe nausea and vomiting caused by various factors, such as after surgery or cancer treatment. It belongs to a class of drugs known as phenothiazines and is not recommended for use in children younger than 2 years or in children going through surgery.
Do's
  • Take Compazine by mouth with or without food as directed by your healthcare provider. 
  • Follow the specific instructions provided by your healthcare provider regarding the administration of Compazine. 
Don'ts
  • Do not take Compazine more frequently than directed by your healthcare provider. 
  • Avoid exceeding the prescribed dosage of Compazine without consulting your healthcare provider. 
The typical dosage of Compazine is usually 5 mg to 10 mg taken orally 3 to 4 times daily. The dosage may be adjusted based on the individual's response and the severity of the condition. For non-psychotic anxiety, the usual dosage is 5 mg 3 to 4 times daily. The dosage is based on your age, medical condition, and response to treatment. In children, the dosage may also be based on weight. 
Common Side Effects:
  • Drowsiness, dizziness, and lightheadedness
  • Blurred vision
  • Constipation
  • Dry mouth
  • Skin reactions
  • Low blood pressure
  • Missed menstrual periods (amenorrhea)
  • Increased appetite and weight gain
  • Agitation, feeling jittery, and trouble sleeping
  • Impotence and abnormal ejaculation
This is not an exhaustive list, and other side effects may occur. If you experience any unusual or severe side effects while taking Compazine,  contact your healthcare provider for medical advice.
Here are some warnings and precautions to consider when taking Compazine:
  1. Elderly patients with dementia: There may be a slightly increased risk of serious, possibly fatal side effects (such as heart failure, fast/irregular heartbeat, pneumonia) when Compazine is used by older adults with dementia. Compazine is not approved for the treatment of dementia-related behavior problems. Discuss the risks and benefits of this medication with your healthcare provider
  2. Allergies and inactive ingredients: Before taking prochlorperazine, inform your healthcare provider if you are allergic to it or other phenothiazines, or if you have any other allergies. Compazine may contain inactive ingredients that can cause allergic reactions or other problems. Talk to your healthcare provider for more details
  3. Pediatric use: Compazine should not be used in pediatric patients under 20 pounds in weight or 2 years of age. Take particular precautions in administering the drug to children with acute illnesses or dehydration.
  4. Hepatotoxicity: Compazine has been associated with hepatotoxicity (liver damage). Regular monitoring of liver function may be necessary in patients taking Compazine.
  5. Neutropenia: Patients with severe neutropenia (low white blood cell count) should discontinue Compazine and have their white blood cell count followed until recovery. 

 

Brand Name:

Compazine
Generic name:

Prochlorperazine, Prochlorperazine
Other Names:

Prochlorazine, Stemetil MD, Prochlorperazine
Strength(s): 5mg, 10mg
Quantities Available: 84, 100
Formulation:

Tablet
PDFCompazine product monograph
Important Information
The information above for Compazine (Prochlorperazine) was provided to DoctorSolve.com by third parties. In no way should this information substitute for the advice of a physician. Consult a doctor or qualified health care professional if you have any medical concerns.
Dr. Zickler

Co-founder of DoctorSolve

Dr. Paul Zickler (Retired)

Dr. Paul Zickler co-founded DoctorSolve™ Health Care Solutions in 1999. He graduated from the faculty of medicine at the University of Western Ontario in 1972 and became an Emergency Physician. He practiced as an Emergency Physician for 18 years after which he co-owned and operated several ambulatory medical and travel clinics for 12 years and discovered his interest in prescription medicines.

More about Dr. Paul Zickler
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