Paxil CR (Paroxetine)

• Before starting Paxil CR and each time you get a refill, read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist. If you have any questions or concerns, consult your healthcare provider.
• The dosage of Paxil CR is determined by your healthcare provider and is based on various factors such as your medical condition, response to treatment, age, and other medications you may be taking. Your healthcare provider may start you on a low dose and gradually increase it to reduce the risk of side effects.
• Paxil CR is taken orally, by mouth. It can be taken with or without food, as directed by your healthcare provider. Taking this medication with food may help decrease nausea.
• If Paxil CR makes you sleepy during the day, you can discuss with your healthcare provider about taking it in the evening.  Swallow the tablets whole.
• To get the most benefit from Paxil CR, take it regularly and at the same time each day. This helps maintain a consistent level of the medication in your body. 
• If you are taking Paxil CR for premenstrual problems, your healthcare provider may direct you to take it every day of the month or just for the 2 weeks before your period through the first full day of your period.
• It may take several weeks before you start experiencing the full benefit of Paxil CR. Continue taking this medication even if you start feeling better.
• If your condition does not improve or if it worsens, inform your healthcare provider as they may need to adjust your treatment plan.

Don’ts

• Do not crush or chew the tablets, as this can release all of the drug at once, increasing the risk of side effects.
• Do not stop taking Paxil CR without consulting your healthcare provider, as suddenly stopping the medication may worsen certain conditions. If your healthcare provider decides to discontinue the treatment, they may gradually reduce your dose to prevent withdrawal symptoms.

• Nausea
• Sleepiness
• Headache
• Ejaculation disturbance

There may be other side effects associated with Paxil CR that are not listed here. Additionally, some side effects may be rare or severe. If you experience any unusual or severe side effects while taking Paxil CR, seek medical attention.

Paxil CR may harm an unborn baby, and babies born to mothers who have used it during the last 3 months of pregnancy may sometimes develop withdrawal symptoms. Discuss the risks and benefits of using Paxil CR during pregnancy with your healthcare provider. 

Paxil CR can pass into breast milk, consult with your healthcare provider before taking Paxil CR while breastfeeding.

Paxil CR is not approved for use in pediatric patients. Adverse reactions have been reported upon discontinuation of treatment with paroxetine in pediatric patients. The safety and effectiveness of Paxil CR in pediatric patients have not been established.

Paxil CR may interact with other medications. Inform your healthcare provider about all the products you use, including prescription drugs, nonprescription drugs, and herbal products. 

Paxil CR and other antidepressant medications may increase the risk of suicidal thoughts and behaviors, especially in children, adolescents, and young adults. Close observation and communication with the healthcare provider are advised, especially during the early stages of treatment or when the dosage is adjusted. Report any new or worsening symptoms to your healthcare provider immediately.

At least 14 days must elapse between discontinuation of an MAOI antidepressant and initiation of Paxil CR. Additionally, at least 14 days must elapse after stopping Paxil CR before starting an MAOI antidepressant. Concomitant use of Paxil CR with MAOIs can lead to serious and potentially life-threatening reactions.

These are not all the warnings and precautions associated with Paxil CR. Consult the prescribing information, medication guide, and your healthcare provider for comprehensive information and guidance.