Otezla (Apremilast)


(Brand Option)

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This brand medication is not available at the moment.


(Generic Alternative)

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FormulationFormulation: Tablet
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$85.00 ($1.42 per tablet)

$97.00 ($1.62 per tablet)

$115.00 ($1.28 per tablet)

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Otezla (apremilast) is indicated for the following conditions:

  1. Psoriatic Arthritis: Otezla is indicated for the treatment of adult patients with active psoriatic arthritis.
  2. Plaque Psoriasis: It is indicated for the treatment of adult patients with plaque psoriasis who are candidates for phototherapy or systemic therapy.
  3. Oral Ulcers Associated with Behet's Disease: Otezla is also indicated for the treatment of adult patients with oral ulcers associated with Behet's Disease.

Otezla works by inhibiting an enzyme within the immune system that can affect certain cells and contribute to inflammation in the body. 


  • Otezla is taken orally in tablet form, with or without food, as directed by a healthcare provider, usually twice daily. 
  • The dosage of Otezla is individualized based on the patient's medical condition and their response to treatment. To minimize the risk of side effects, your healthcare provider may recommend starting with a low dose and gradually increasing it as directed.
  • Use Otezla regularly as prescribed to achieve the maximum benefits. Taking it at the same times each day can help in ensuring consistent treatment.
  • Inform your healthcare provider if there is no improvement in your condition or if it worsens while taking Otezla.


  • The tablets should not be crushed, split, or chewed before ingestion.

Common and Mild Side Effects:

  • Nausea
  • Diarrhea
  • Headache
  • Cold symptoms such as stuffy nose, sneezing, and sore throat 

Mild side effects are usually temporary and may improve after a few weeks of treatment.

Serious Side Effects:

  • Severe diarrhea
  • Nausea
  • Vomiting
  • Unexplained weight loss
  • Mood changes
  • New or worsening depression
  • Thoughts of suicide or self-harm
  • Allergic reactions 

Severe allergic reactions may manifest as trouble breathing or swallowing, raised bumps (hives), rash or itching, and swelling of the face, lips, tongue, throat, or arms.

Inform your healthcare provider about any side effect that bothers you or does not go away.

Hypersensitivity reactions, including angioedema and anaphylaxis, have been reported during postmarketing surveillance. If signs or symptoms of serious hypersensitivity reactions occur, discontinue Otezla and seek appropriate medical therapy.

Otezla is contraindicated in patients with a known hypersensitivity to apremilast or to any of the excipients in the formulation.

Certain medications may interact with Otezla. Inform the healthcare provider about all current medicines and any new medications being started or stopped. Specific interactions with medications such as carbamazepine, enzalutamide, fosphenytoin, and mitotane may require dose adjustments or other precautions.

Otezla has not been studied in pregnant women. Therefore, it's essential to advise pregnant women of the potential risk of fetal loss and to consult a healthcare provider before using Otezla if pregnant or planning to become pregnant.

Generic name:




Strength(s): 10mg, 20mg, 30mg
Quantities Available: 60, 90
Important Information
The information above for Otezla (Apremilast) was provided to DoctorSolve.com by third parties. In no way should this information substitute for the advice of a physician. Consult a doctor or qualified health care professional if you have any medical concerns.
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