Bonefos (Clodronate Disodium)

Bonefos is used to treat hypercalcemia (high blood calcium) in people with cancer and to treat cancer that has spread to bones (bone metastases) due to different types of tumors.

Bonefos, also known as clodronate, belongs to a family of medications known as bisphosphonates.

Clodronate works by slowing down the breakdown of bone and lowering the amount of calcium lost from the bones. This mechanism helps in reducing the impact of bone metastases and hypercalcemia in cancer patients.

Do’s

• Take Bonefos exactly as prescribed by your healthcare provider. This includes the dosage (amount), frequency (how often you take it), and duration (for how long).
• Read the Patient Information Leaflet that comes with the medication. This will provide important information about side effects, drug interactions, and storage instructions.
• Take it on an empty stomach, with a full glass of water. This is usually at least two hours before a meal or any drinks except water.
• Sit upright or stand for at least 30 minutes after taking the capsule. Avoid lying down or reclining to prevent heartburn.
• Maintain good dental hygiene. It can affect your jawbone, so see your dentist for regular checkups and cleanings.

Don'ts

• Do not take more of this medication than prescribed by your healthcare provider.
• Do not take this medication if you are allergic to pamidronate or any of its ingredients.
• Do not take this medication with milk, dairy products, calcium supplements, or mineral supplements, as these may interfere with its absorption.
• Do not take this medication with other medications without consulting your healthcare provider. This includes prescription and over-the-counter medications, as well as vitamins and herbal supplements.
• Do not crush, chew, or dissolve the capsule. Swallow it whole.
• Do not become pregnant or breastfeed while taking this medication. Discuss with your healthcare provider if you plan to become pregnant.

Side Effects

Common Side Effects:

• Gastrointestinal disturbances
• Fatigue
• Headache
• Nausea
• Diarrhea

Serious Side Effects:

• Osteonecrosis of the jaw
• Atrial fibrillation
• Renal impairment
• Hypocalcemia
• Ocular inflammation

This is not a complete list of possible side effects. For a complete list, ask your doctor or pharmacist.

Warnings

Known allergy to clodronate or any other ingredients in Bonefos.

A diagnosed seizure disorder or a suspected increased risk of seizures.

Recently taken monoamine oxidase inhibitors (MAOIs). You should wait at least 14 days after stopping MAOIs before starting Bonefos treatment due to the potential for serious interactions.

Talk to your healthcare provider before using Bonefos if you have any of the following medical conditions:

• Heart problems: A history of heart attack, irregular heartbeat (arrhythmias), or other cardiovascular issues. Bonefos may affect heart rhythm.
• Kidney problems: Reduced kidney function can affect how your body processes Bonefos.
• Liver problems: This may affect how your body metabolizes Bonefos.
• Esophageal problems: A history of ulcers or inflammation in the esophagus (the tube connecting your throat to your stomach). Bonefos can irritate the esophagus.

Follow your healthcare provider's instructions carefully for taking Bonefos, including the dosage and administration method. Bonefos is usually taken with a full glass of water while sitting upright and remains upright for at least 30 minutes after taking it.

Do not lie down for at least 30 minutes and avoid eating food until after taking Bonefos.

Ii can decrease the absorption of other medications. Inform your healthcare provider about all medications you are taking, including prescription drugs, over-the-counter medications, vitamins, and herbal products. Your healthcare provider may need to adjust the timing of your medications.

Dental procedures: Inform your dentist that you are taking Bonefos before undergoing any dental procedures.

Pregnancy and Breastfeeding: It should only be used during pregnancy if clearly necessary. Discuss the risks and benefits with your healthcare provider. Bonefos may pass into breast milk, so consult your healthcare provider before breastfeeding while taking Bonefos.

Bonefos may weaken your bones with long-term use. Your healthcare provider will monitor your bone health with regular tests.

Where To Buy Bonefos?

Bonefos is not available in the US. You can purchase it from online Canadian pharmacies. Canadian pharmacies offer competitive pricing on Bonefos. DoctorSolve is a certified online pharmacy intermediary that connects you with licensed Canadian pharmacies, providing access to safe and genuine Bonefos at lower costs. Simply add Bonefos with your required dosage and pack size to your cart, submit your valid prescription, and your order will typically arrive within 2-4 weeks.

How Much Does Bonefos Cost?

Bonefos is currently discontinued or unavailable for purchase in the United States, making it challenging for customers who rely on this medication to manage their condition. However, Canadian pharmacies continue to offer Bonefos, providing a viable solution for Americans seeking access to this important treatment. Through DoctorSolve.com, customers can obtain Bonefos from licensed Canadian pharmacies. A 120 supply of 400mg Bonefos is available for approximately $299.00. This provides continuity of care for customers whose treatment depends on this medication.

Can I buy Bonefos over the counter?

No, you cannot buy Bonefos over the counter in the United States. Its active ingredient, clodronate, is used for bone disorders and requires supervision. It may cause serious side effects such as low calcium levels and kidney problems.