Estrace (Estradiol)

Do's

• Take Estrace exactly as directed by your healthcare provider, including timing (with or without food) and dosage. 
• Swallow extended-release tablets whole. 
• Take Estrace regularly at the same time(s) each day for maximum benefit. 
• Inform your healthcare provider if your condition doesn't improve or worsens while taking Estrace. 

Don'ts

• Do not crush, chew, or dissolve extended-release tablets. This can release all the medication at once, increasing side effects. 
• Do not adjust your dose or take Estrace more often or for longer than prescribed. 

Systemic absorption may occur with the use of Estrace. The warnings, precautions, and adverse reactions associated with oral estrogen treatment should be taken into account. The following adverse reactions have been reported with estrogen and/or progestin therapy.

1. Genitourinary System - Abnormal uterine bleeding or spotting; dysmenorrhea or pelvic pain, increase in size of uterine leiomyomata; vaginitis, including vaginal candidiasis; change in cervical secretion; cystitis-like syndrome; application site reactions of vulvovaginal discomfort including burning and irritation; genital pruritus; ovarian cancer; endometrial hyperplasia; endometrial cancer.
2. Breasts - Tenderness, enlargement, pain, nipple discharge, fibrocystic breast changes; breast cancer.
3. Cardiovascular - Deep and superficial venous thrombosis; pulmonary embolism; myocardial infarction; stroke; increase in blood pressure.
4. Gastrointestinal - Nausea, vomiting; abdominal cramps, bloating; increased incidence of gallbladder disease.
5. Skin - Chloasma that may persist when drug is discontinued; loss of scalp hair; hirsutism; rash.
6. Eyes - Retinal vascular thrombosis, intolerance to contact lenses.
7. Central Nervous System - Headache, migraine, dizziness, mental depression, nervousness, mood disturbances, irritability, dementia.
8. Miscellaneous - Increase or decrease in weight, glucose intolerance, edema, arthralgias, leg cramps, changes in libido, urticaria, exacerbation of asthma, increased triglycerides, hypersensitivity.

Side Effects

Common Side Effects:

• Nausea, vomiting, diarrhea, stomach cramps
• Mood changes, sleep problems (insomnia)
• Cold symptoms such as stuffy nose, sinus pain, sore throat
• Breast pain
• Thinning scalp hair
• Vaginal itching or discharge, changes in menstrual periods, breakthrough bleeding

Serious Side Effects:

• Chest/jaw/left arm pain
• Unusual sweating
• Sudden/severe headache
• Weakness on one side of the body
• Confusion
• Trouble speaking
• Sudden vision changes (such as partial/complete blindness)
• Pain/redness/swelling of legs
• Tingling/weakness/numbness in the arms/legs
• Trouble breathing
• Coughing up blood
• Sudden dizziness/fainting
• Allergic reactions such as rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing

This is not an exhaustive list, and other side effects may occur. If you experience any unusual or severe side effects while taking  Estrace,  contact your healthcare provider for medical advice.

Can you buy Estrace over the counter?

No, you cannot buy Estrace over the counter because it is a prescription drug that requires medical supervision. Since it can cause serious side effects such as blood clots, stroke, or hormone-related complications, a doctor must monitor its use to ensure safety.

How much does Estrace cost?

The cost of Estrace varies based on factors such as dosage and pack size. In the United States, an 84-tablet pack of 1 mg Estrace costs over $538.14 on average at major retail pharmacy chains [1]. If you're looking for a more affordable option, Canadian pharmacies offer significantly lower prices. Through DoctorSolve.com, the same 84-tablet pack is available for approximately $48 — a savings of around 91% compared to U.S. retail prices. This makes Canadian pharmacies an excellent choice for those seeking cost-effective access to their prescription medications.

Where can I buy Estradiol?

Estradiol (the generic form of Estrace) is available at most pharmacies with a valid prescription from your doctor. You can purchase it at local retail pharmacies or through online pharmacy services. If you're looking for a more affordable option, Canadian pharmacies offer competitive pricing on this medication. DoctorSolve is a certified online pharmacy intermediary that connects you with licensed Canadian pharmacies, providing access to safe and genuine estradiol at lower costs. Simply add the medication with your required dosage and pack size to your cart, submit your valid prescription, and your order will typically arrive within 2-4 weeks.

How much does Estradiol cost?

The cost of Estradiol varies based on factors such as dosage and pack size. In the United States, a 100-tablet pack of 1 mg Estradiol costs over $106.46 on average at major retail pharmacy chains [1]. If you're looking for a more affordable option, Canadian pharmacies offer significantly lower prices. Through DoctorSolve.com, the same 100-tablet pack is available for approximately $70 — a savings of around 34% compared to U.S. retail prices. This makes Canadian pharmacies an excellent choice for those seeking cost-effective access to their prescription medications.

Is Estradiol available in Canada?

Estradiol is available in Canada through licensed Canadian pharmacies, offering a safe and affordable alternative for Americans seeking this prescription medication. Estradiol purchased from Canadian pharmacies often costs significantly less than U.S. prices, making it an attractive option for those managing their healthcare expenses.