Tolak Cream (Fluorouracil)

Tolak Cream

(Brand Option)

Prescription RequiredPrescription Required
FormulationFormulation: Cream
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(Generic Alternative)

Prescription RequiredPrescription Required

This generic medication is not available at the moment.

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Tolak Cream, also known as fluorouracil cream, is indicated for the topical treatment of actinic keratosis lesions of the face, ears, and/or scalp in adults. Actinic keratosis is a rough, scaly patch on the skin that develops from years of exposure to the sun.


  • Before applying Tolak Cream, clean the affected area and ensure it is thoroughly dry. Wait for 10 minutes, then apply a small amount of the medication to the affected skin, using just enough to cover the area with a thin film.
  • The cream should be applied once daily to the areas of the skin to be treated for a period of 4 weeks unless otherwise directed by a healthcare provider.
  • Use the medication exactly as prescribed. 
  • After applying Tolak Cream, wash your hands immediately, even if gloves have been used.
  • The treated area may become unsightly during treatment and for several weeks after treatment. Consult with a healthcare provider regarding the possibility of loosely covering the treated area with gauze.
  • Tolak Cream may cause serious harm, even death, to pets. It should be kept securely away from pets. In case of pet contact, a veterinarian should be contacted immediately.


  • Do not stop using this cream without consulting a healthcare provider. 
  • Increasing the dose or using this cream more often than directed is not recommended, as it may lead to increased side effects without accelerating the clearing of the condition.
  • Do not cover the treated area with tight dressings or plastic bandages.
  • Avoid applying the medication in or around the eyes or eyelids, as well as inside the nose or mouth. If accidental contact occurs in these areas, it should be rinsed with plenty of water.
  • Pets should not be allowed to lick the area where the medication was applied.

Common Side Effects:

  • Skin reactions at the site of application, such as irritation, pain, redness, itching, inflammation, and swelling 

Serious Side Effects: 

  • Severe stomach-area (abdominal) pain
  • Bloody diarrhea
  • Vomiting
  • Fever
  • Chills 

Stop using Tolak Cream and call your healthcare provider at once if you experience serious side effects.

This is not an exhaustive list of side effects, and individuals should consult their healthcare provider for further information and advice.

Tolak Cream is associated with photosensitivity reactions, including severe sunburn. Patients are advised to minimize exposure to the sun, sun lamps, and tanning beds while using Tolak Cream. Sunscreens may be applied after Tolak Cream application to protect the treated area from sun exposure.

Tolak Cream is not for ophthalmic use. 

Females of reproductive potential should be informed of the potential risk to a fetus. Effective contraception should be used during and for one month after the last dose of Tolak Cream. Additionally, healthcare providers should be informed of any known or suspected pregnancy.

Patients should discontinue Tolak Cream immediately and seek medical attention if signs of severe hypersensitivity occur.

Other skin products should not be used while using Tolak Cream unless instructed by a healthcare provider.

Patients should not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard the product when it is expired or no longer needed.

Individuals using Tolak Cream should adhere to these warnings and precautions to ensure the safe and effective use of the medication. If there are any concerns or questions, consult a healthcare provider for personalized guidance.

Brand Name:

Tolak Cream

Generic name:


Other Names:

Tolak Cream

Strength(s): 4%
Quantities Available: 40


Important Information
The information above for Tolak Cream was provided to by third parties. In no way should this information substitute for the advice of a physician. Consult a doctor or qualified health care professional if you have any medical concerns. widget logo
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