Lotriderm Cream (Clotrimazole/Betamethasone Dipropionate)

Lotriderm Cream

(Brand Option)

Prescription RequiredPrescription Required
FormulationFormulation: Cream
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Clotrimazole/Betamethasone Dipropionate

(Generic Alternative)

Prescription RequiredPrescription Required
FormulationFormulation: Cream
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Lotriderm Cream is used to treat itchy, inflamed skin rashes caused by certain types of fungus, such as athlete's foot, jock itch, and ringworm. 

Lotriderm is a combination product containing two medications: betamethasone and clotrimazole. Betamethasone belongs to the group of medications called corticosteroids and works by decreasing inflammation. The clotrimazole component of the cream treats the fungal infection, while the betamethasone reduces the associated redness and itching.


  • Wash your hands thoroughly with soap and water before and after applying Lotriderm Cream. Washing hands with soap and water is generally recommended before applying any topical medication]
  • Clean and dry the affected area before applying the cream.
  • Apply a thin film of Lotriderm Cream to the affected area as directed by your healthcare provider.
  • Don't bandage the treated area unless specifically instructed by your healthcare provider.
  • Use the medication for the full prescribed course even if symptoms improve. Stopping the medication early may allow the infection to return.


  • Don't use Lotriderm Cream if you are allergic to any of its ingredients.
  • Don't apply Lotriderm Cream to your eyes, nose, or mouth.
  • Don't use Lotriderm Cream on large areas of skin, especially for extended periods, unless directed by your healthcare provider.
  • Don't use Lotriderm Cream with other topical medications without consulting your healthcare provider.
  • Don't use Lotriderm Cream if the package is opened or tampered with.

Common side effects

  • Burning or stinging at the application site
  • Itching
  • Redness
  • Dryness
  • Rash

Serious side effects

  • Thinning of the skin
  • Stretch marks
  • Changes in skin color (darkening or lightening)
  • Acne
  • Excessive hair growth
  • Blurred vision
  • Cushing's syndrome (a condition that causes weight gain, rounded face, and high blood pressure)

This is not an exhaustive list, and other side effects may occur. If you experience any unusual or severe side effects while taking Lotriderm cream,  contact your healthcare provider for medical advice.

Lotriderm is not formulated for ophthalmic use and can worsen eye problems.

Using Lotriderm cream for longer than 4 weeks without a healthcare provider's guidance increases the risk of side effects.

Consult a healthcare provider before using Lotriderm for extensive or severe infections.

Disclose any allergies to clotrimazole, betamethasone, or other Lotriderm ingredients.

Inform your healthcare provider about any existing skin conditions, particularly rosacea or perioral dermatitis, as Lotriderm may worsen them.

Discuss the risks and benefits of using Lotriderm cream with your healthcare provider if you are pregnant or breastfeeding.

Inform your healthcare provider about all medications you take, including prescription drugs, over-the-counter medications, vitamins, and herbal products, to avoid potential interactions.


Generic name:

Clotrimazole/Betamethasone Dipropionate, Clotrimazole/Betamethasone Dipropionate



Strength(s): 1%/0.05%
Quantities Available: 15, 45, 50
Important Information
The information above for Lotriderm Cream (Clotrimazole/Betamethasone Dipropionate) was provided to DoctorSolve.com by third parties. In no way should this information substitute for the advice of a physician. Consult a doctor or qualified health care professional if you have any medical concerns.
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