Iopidine Eyedrops (Apraclonidine hydrochloride)

Iopidine Eyedrops

(Brand Option)

Prescription RequiredPrescription Required
FormulationFormulation: Drops
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Apraclonidine hydrochloride

(Generic Alternative)

Prescription RequiredPrescription Required

This generic medication is not available at the moment.

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Iopidine (apraclonidine) is a type of eye drop that belongs to the class of alpha agonists. It is primarily indicated for the treatment of elevated intraocular pressure (IOP), which

is often associated with conditions such as glaucoma.


  • Iopidine Eyedrops are typically used in the affected eye(s) as directed by your healthcare provider, usually three times daily. The usual dose is one to two drops in each affected eye. 
  • Before applying the eye drops, ensure your hands are clean to avoid contamination.
  • If you wear contact lenses, remove them before using the eye drops. Wait at least 15 minutes before replacing your contact lenses.
  • To apply the eye drops, tilt your head back, look up, and pull down the lower eyelid to make a pouch. Hold the dropper directly over your eye and place one drop into the pouch. Release the eyelid and gently close your eyes. Place one finger at the corner of your eye (near the nose) and apply gentle pressure for 1 to 2 minutes. This will prevent the medication from draining out. Repeat these steps for your other eye if so directed or if your dose is for more than one drop.
  • After using Iopidine Eyedrops, remove any extra solution around the eye with a tissue and wash your hands to remove any medicine that may be on them.
  • If you are using another kind of eye medication (such as drops or ointments), wait at least 5 minutes before using the other medication. Use eye drops before ointments to allow the eye drops to enter the eye.
  • Wait several minutes for your vision to clear before driving or operating machinery.
  • Your dosage is based on your medical condition and response to treatment.  When used for an extended time, this medication may not work as well and may require different dosing. Your healthcare provider will monitor your progress with regular eye exams.


  • Do not use Iopidine Eyedrops in larger or smaller amounts or for longer than recommended.
  • Do not touch the dropper tip or let it touch your eye or any other surface.
  • Do not blink and do not rub your eye after applying the eye drop.

Ocular Side Effects: 

  • Dry or watery eyes
  • Blurred vision
  • Eye discomfort or irritation
  • Redness of the eyes
  • A sensation of a foreign body in the eye
  • Swelling of the eyelids and conjunctiva

Systemic Side Effects:

  • Drowsiness
  • Dizziness
  • Headache

Consult your healthcare provider if you experience any of these side effects or if they persist or worsen over time. Your healthcare provider will be able to provide guidance and determine the best course of action.

This is not an exhaustive list of side effects, and other side effects may occur. Consult with your healthcare provider for more information about the potential side effects of Iopidine Eyedrops.

Iopidine Eyedrops may interact with other medications you are taking. Inform your healthcare provider about all the medications, including prescription and over-the-counter drugs, as well as any herbal supplements or vitamins, that you are currently using. They can assess potential interactions and provide guidance.

If you have a known allergy to Iopidine or any of its components, avoid using this medication. Allergic reactions can range from mild to severe and may include symptoms such as rash, itching, swelling, dizziness, or difficulty breathing. Seek immediate medical attention if you experience any signs of an allergic reaction.

Inform your healthcare provider about any pre-existing medical conditions you have, especially blood vessel disease, high blood pressure, heart problems, kidney disease, liver disease, or mental/mood disorders. These conditions may require special precautions or adjustments in the use of Iopidine Eyedrops.

The safety of Iopidine Eyedrops during pregnancy and breastfeeding has not been established. If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider before using this medication.

Iopidine Eyedrops should be used as directed by your healthcare provider. Do not stop using the medication without consulting your healthcare provider, as sudden discontinuation may have adverse effects.

This is not an exhaustive list of warnings and precautions associated with Iopidine Eyedrops. Consult with your healthcare provider or pharmacist for more specific information based on your individual circumstances.

Brand Name:

Iopidine Eyedrops

Generic name:

Apraclonidine hydrochloride

Other Names:

Iopidine Eyedrops

Strength(s): 0.5%
Quantities Available: 5, 10


Important Information
The information above for Iopidine Eyedrops (Apraclonidine hydrochloride) was provided to by third parties. In no way should this information substitute for the advice of a physician. Consult a doctor or qualified health care professional if you have any medical concerns. widget logo
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