Duaklir Pressair (Aclidinium Bromide/Formoterol Fumarate)

Do’s

• Use it exactly as directed by your healthcare provider. This includes dosage (usually twice daily), frequency (morning and evening), and inhalation technique (inhalation by mouth, not eyes).
• Use it regularly at the same times each day to maximize the benefit.
• Maintain a consistent schedule and avoid increasing the dose or using it more often without consulting your healthcare provider.
• Follow your healthcare provider's instructions regarding other inhalers, especially if you are using a quick-relief inhaler regularly. You might need to switch to using it only "as needed" for sudden breathing problems.
• Learn which inhaler is for daily use and which is for quick relief.
• Develop an action plan with your healthcare provider for worsening symptoms, increased quick-relief inhaler use, or loss of effectiveness of the quick-relief inhaler. This plan should include when to seek medical attention.
• Inform your healthcare provider if your condition doesn't improve or worsens.

Don'ts

• Don't increase your dose or use it more often without consulting your healthcare provider.
• Don't stop using it without talking to your healthcare provider first.
• Don't exhale into the device.
• Don't get any medication in your eyes.
• Don't use your quick-relief inhaler on a regular schedule unless your healthcare provider instructs you to do so.

Common side effects:

• Upper respiratory tract infection (common cold)
• Headache
• Back pain
• Cough
• Sinusitis (inflammation of the sinuses)
• Influenza (flu)
• Tooth abscess
• Insomnia (trouble sleeping)
• Dizziness
• Dry mouth
• Sore throat
• Muscle spasms
• Musculoskeletal pain (muscle or bone pain)
• Joint pain
• Pain in extremities
• Urinary tract infection (UTI)
• Increased blood creatine phosphokinase (a muscle enzyme)

Serious side effects:

• Difficulty breathing, wheezing, choking, or other breathing problems
• Worsening breathing problems.
• Tremors
• Nervousness
• Chest pain
• Fast or pounding heartbeats.
• High blood pressure
• Blurred vision, tunnel vision, eye pain or redness, or seeing halos around lights are potential side effects.
• Signs of a serious allergic reaction: These include rash, itching, swelling of the face, lips, tongue, or throat, severe dizziness, or trouble breathing.
• Painful or difficult urination, or urinating more often
• Muscle cramps or weakness

This is not an exhaustive list, and other side effects may occur. If you experience any unusual or severe side effects while taking Duaklir pressair,  contact your healthcare provider for medical advice.

Inform your healthcare provider if you have allergies to aclidinium, formoterol, milk proteins, or any ingredients in Duaklir Pressair.

Discuss your medical history with your healthcare provider before using Duaklir Pressair, especially regarding:

• Heart problems (chest pain, irregular heartbeat)
• High blood pressure
• Seizures
• Overactive thyroid
• Diabetes
• Glaucoma (angle-closure type)
• Difficulty urinating (enlarged prostate)
• Pheochromocytoma (adrenal gland tumor)

Duaklir Pressair may cause irregular heartbeat (QT prolongation). This is a serious but rare side effect.

The risk increases with certain medical conditions or medications. Inform your healthcare provider about any relevant conditions or medications you take.

Low blood potassium or magnesium levels can also increase the risk.

Inform your healthcare provider or dentist about all medications you use, including Duaklir Pressair, before surgery.

Older adults may be more susceptible to QT prolongation with Duaklir Pressair (see point 3).

Duaklir Pressair should only be used during pregnancy if absolutely necessary. Discuss risks and benefits with your healthcare provider.

It is unknown if Duaklir Pressair passes into breast milk. Consult your healthcare provider before breastfeeding.