Combivir (Lamivudine/zidovudine)


(Brand Option)

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FormulationFormulation: Tablet
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$899.00 ($14.98 per tablet)


(Generic Alternative)

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FormulationFormulation: Tablet
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$89.00 ($1.48 per tablet)

$149.00 ($1.24 per tablet)

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Combivir is a combination product containing two drugs: lamivudine and zidovudine. It is used along with other HIV medications to help control HIV infection.

Both lamivudine and zidovudine belong to a class of drugs called nucleoside reverse transcriptase inhibitors (NRTIs). The medication works by decreasing the amount of HIV in the body, allowing the immune system to function better. This reduces the risk of HIV complications and improves quality of life.

Combivir is not a cure for HIV infection. To reduce the risk of spreading HIV to others, continue taking all HIV medications exactly as prescribed by a healthcare provider. Barrier methods, such as latex or polyurethane condoms and dental dams, should be used during sexual activity as directed by a healthcare provider.


  • Take Combivir exactly as prescribed by your healthcare provider, typically twice daily.
  • Take it with a full glass of water (8oz/240ml) unless your healthcare provider advises otherwise.
  • Continue taking Combivir consistently, even if you feel well. Don't skip doses.
  • Maintain a consistent schedule - take it at the same time each day to aid memory.


  • Don't adjust your dosage or take Combivir more often than prescribed.
  • Don't stop taking Combivir (or other HIV medications) without consulting your healthcare provider, even briefly. Stopping mid-treatment can worsen your condition or lead to drug resistance.
  • Don't take Combivir if you weigh less than 30 kilograms (66 pounds).

Combivir is a combination medication with fixed doses. It's not suitable if your healthcare provider determines you need different dosages of lamivudine and zidovudine (the two components).

Common Side Effects:

  • Nausea
  • Vomiting
  • Headache
  • Fatigue
  • Insomnia
  • Dizziness
  • Diarrhea
  • Fever
  • Muscle pain
  • Rash

Serious Side Effects:

  • Blood disorders (e.g., anemia, neutropenia)
  • Lactic acidosis (buildup of lactic acid in the body)
  • Liver problems (elevated liver enzymes)
  • Pancreatitis (inflammation of the pancreas)
  • Peripheral neuropathy (nerve damage causing tingling or numbness in extremities)
  • Changes in body fat distribution (lipodystrophy)
  • Allergic reactions (rare but can be severe)

This is not an exhaustive list, and other side effects may occur. If you experience any unusual or severe side effects while taking Combivir,  contact your healthcare provider for medical advice.

Tell your healthcare provider if you are allergic to lamivudine, zidovudine, or any other ingredients in Combivir.

Inform your healthcare provider about any pre-existing health problems, especially kidney disease, liver problems, pancreatitis, alcohol use, or low blood cell counts.

Combivir may cause dizziness. Avoid driving, operating machinery, or activities requiring alertness until you feel safe. Limit alcohol and marijuana use, which can worsen dizziness.

Limit alcohol consumption to reduce the risk of liver problems and pancreatitis, a side effect that can be more severe in children.

Inform your healthcare provider about all medications you take, including Combivir, before any surgery.

Combivir can help reduce the risk of transmitting HIV to your baby. Discuss the risks and benefits with your healthcare provider.

Combivir passes into breast milk. Consult your healthcare provider before breastfeeding as HIV can be transmitted through breast milk.

Brand Name:


Generic name:

Lamivudine/zidovudine, Lamivudine/Zidovudine

Other Names:

Combivir, Duovir

Strength(s): 150/300mg
Quantities Available: 60, 120


Important Information
The information above for Combivir (Lamivudine/Zidovudine) was provided to by third parties. In no way should this information substitute for the advice of a physician. Consult a doctor or qualified health care professional if you have any medical concerns. widget logo
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