Apoquel (Oclacitinib)


(Brand Option)

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FormulationFormulation: Tablet
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$140.00 ($2.33 per tablet)

$155.00 ($2.58 per tablet)

$320.00 ($3.20 per tablet)


(Generic Alternative)

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This generic medication is not available at the moment.

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Apoquel is indicated for the control of pruritus from allergic dermatitis and atopic dermatitis in dogs that are at least 12 months old. It is specifically designed to treat itching and inflammation in dogs by targeting important itch signals in their bodies, helping to stop the itch before it starts. Apoquel starts working within 4 hours and helps stop itching within 24 hours. Veterinarians may prescribe Apoquel either short-term for allergic flare-ups or long-term for the management of skin allergies.


  • Administer Apoquel orally to dogs as prescribed.  
  • Obtain Apoquel in tablet form and administer it according to the veterinarian's prescription. 
  • Follow the prescribed dosage and administration instructions provided by the veterinarian for the dog's specific needs.  
  • Consult a veterinarian for proper guidance and prescription before using Apoquel for your pet.   


  • Avoid using Apoquel twice daily for longer than 14 days. 
  • Do not exceed the recommended dose of Apoquel as the dose range is very strict due to immune suppression. 
  • Don't use a dose below the recommended range of Apoquel, as it may not effectively address the dog's condition in most cases. 

The recommended initial dose of Apoquel is 0.4-0.6 mg/kg every 12 hours for up to 14 days, then 0.4-0.6 mg/kg once daily thereafter. 

  • Vomiting
  • Diarrhea
  • Lethargy
  • Decreased appetite
  • Bloodwork changes, especially decreased blood cell counts
  • Increased risk of infections, such as urinary tract infections, skin infections, and respiratory infections
  • Exacerbation of existing tumors/cancer
  • Gastrointestinal side effects
  • Skin and ear infections
  • Demodicosis
  • Neoplasia
  • Pneumonia
  • Bloody diarrhea
  • Histiocytomas
  • Polydipsia
  • Increased appetite
  • Aggression

The side effects mentioned above are based on reported experiences and observations. Dog owners should consult with a veterinarian before administering Apoquel to their pets, and closely monitor their dogs for any adverse reactions or changes in behavior while on the medication.

Apoquel is not for use in dogs less than 12 months of age. Additionally, it should not be used in dogs with serious infections, as it may increase the chances of developing serious infections and exacerbate existing parasitic skin infestations or pre-existing cancers.

Apoquel may increase susceptibility to infection, including demodicosis, and exacerbate neoplastic conditions. New neoplastic conditions (benign and malignant) were observed in dogs treated with Apoquel during clinical studies and have been reported in the post-approval period.

It is possible for dogs to overdose on Apoquel, so it should be kept out of reach of dogs, and all other medications and veterinary advice should be sought immediately if an overdose is suspected.

Apoquel is considered safe to use along with some medications like antihistamines, antibiotics, and NSAIDs. However, caution should be exercised when using it with steroids and immunosuppressive drugs.Apoquel is not for human use, and it should be kept out of reach of children. Hands should be washed immediately after handling the tablets.

Consult a veterinarian for personalized guidance and to address any concerns regarding the use of Apoquel for your dog.

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Strength(s): 3.6mg, 5.4mg, 16mg
Quantities Available: 60, 100


Important Information
The information above for Apoquel (Oclacitinib) was provided to DoctorSolve.com by third parties. In no way should this information substitute for the advice of a physician. Consult a doctor or qualified health care professional if you have any medical concerns.
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