Simbrinza Ophthalmic Suspension (Brinzolamide/Brimonidine)

Do’s

• Use Simbrinza exactly as directed by your healthcare provider, typically 3 times daily.
• Shake the bottle well before each dose.
• Wash your hands thoroughly before applying the drops.
• If you wear contact lenses, remove them before using Simbrinza and wait at least 15 minutes before reinserting them.
• Tilt your head back, look upwards, and pull down your lower eyelid to create a pouch.
• Instill one drop of Simbrinza into the pouch formed by your lower eyelid.
• Gently close your eyes and apply pressure to the inner corner of your eye for 1-2 minutes. This helps prevent drainage.
• Repeat these steps for your other eye if directed.
• Use Simbrinza consistently at the same time(s) each day.
• Continue using Simbrinza even if you feel well. Glaucoma often has no symptoms.

Don'ts

• Don't use more Simbrinza than prescribed by your healthcare provider.
• Don't allow the dropper tip to touch your eye or any other surface to prevent contamination.
• Avoid touching the dropper tip to your eye or any other surface.
• Do not rinse the dropper after use. Replace the cap securely.
• Don't use Simbrinza with other eye medications within 5 minutes of each other. Apply eye drops before eye ointments.
• Don't drive or operate machinery until your vision clears after using Simbrinza.
• Don't stop using Simbrinza without consulting your healthcare provider.

Common side effects of Simbrinza Ophthalmic Suspension may include:

• Eye irritation or discomfort
• Blurred vision
• Dry eyes
• Redness or itching of the eyes
• Unusual taste in the mouth
• Headache
• Dizziness

Serious side effects of Simbrinza Ophthalmic Suspension are rare but may include:

• Rash, itching, swelling (especially of the face, tongue, or throat), severe dizziness, or difficulty breathing.
• Shortness of breath or coughing
• While using Simbrinza Ophthalmic Suspension

This is not an exhaustive list, and other side effects may occur. If you experience any unusual or severe side effects while taking Simbrinza ophthalmic suspension, contact your healthcare provider for medical advice.

Let your healthcare provider know if you have allergies to Simbrinza (apraclonidine) or any other ingredients in the medication.

Inform your healthcare provider about any pre-existing health issues, particularly blood vessel diseases, blood circulation problems, depression, heart disease, kidney disease, liver disease, Raynaud's disease, or low blood pressure upon standing.

Simbrinza may cause dizziness or drowsiness and may blur your vision temporarily after application. Avoid driving, operating machinery, or activities requiring alertness or clear vision until these effects subside. Limit alcohol consumption and discuss marijuana use with your healthcare provider as these can worsen these side effects.

Consult your healthcare provider about using a new bottle of Simbrinza if you experience an eye infection, injury, or have eye surgery.

Inform your healthcare provider about all medications you take (including Simbrinza) before any surgery.

Children may be more sensitive to the side effects of this medication, especially drowsiness.

Simbrinza should only be used during pregnancy if absolutely necessary. Discuss risks and benefits with your healthcare provider.

It is unknown if Simbrinza passes into breast milk. Consult your healthcare provider before breastfeeding.