Jardiance (Empagliflozin)

Do's

• Before starting Jardiance, read the Medication Guide provided by your pharmacist. If you have any questions, ask your healthcare provider for clarification.
• Take this medication by mouth with or without food as directed by your healthcare provider. Typically, it is taken once daily in the morning.
• The dosage of Jardiance is based on your medical condition and your response to treatment. Your healthcare provider will determine the appropriate dosage for you.
• Use this medication regularly to obtain the most benefit from it. Taking it at the same time each day can help you remember to use it consistently.
• Inform your healthcare provider if your condition does not improve or if it worsens. Regular communication with your healthcare provider is essential for monitoring your response to the medication.

Common Side Effects:

• Bladder pain
• Bloody or cloudy urine
• Change in the color, amount, or odor of vaginal discharge
• Difficult, burning, or painful urination
• Frequent urge to urinate
• Itching, stinging, or redness of the vaginal area
• Lower back or side pain
• Pain during sexual intercourse
• Mild urinary tract infection (UTI)
• Mild genital yeast infection
• Urinating more often than usual
• Increased urination
• Elevated levels of fats or cholesterol in the blood
• Joint pain
• Nausea
• Kidney problems

Less Common Side Effects:

• Discharge with a strong odor from the penis

Serious Side Effects:

• Dehydration, with symptoms such as feeling dizzy or lightheaded
• Low blood pressure
• Low blood sugar
• Ketoacidosis (too much acid in the blood)
• Acute kidney impairment or injury
• Allergic reactions 

This is not an exhaustive list of side effects, and other side effects may occur. If you experience any unusual symptoms or side effects while taking Jardiance, seek medical advice promptly.

Always consult your healthcare provider for personalized information and guidance regarding the potential side effects of Jardiance.

Jardiance can cause intravascular volume contraction and may lead to renal impairment. There have been reports of acute kidney injury, some requiring hospitalization and dialysis, in patients receiving SGLT2 inhibitors, including Jardiance. 

Patients should be assessed for signs and symptoms of metabolic acidosis for ketoacidosis, regardless of blood glucose level. Before initiating Jardiance, consider risk factors for ketoacidosis. Patients on Jardiance may require monitoring and temporary discontinuation of therapy in clinical situations known to predispose to ketoacidosis.

Symptomatic hypotension may occur with Jardiance, and patients should be advised to maintain adequate fluid intake to reduce the risk of hypotension.

Jardiance may lead to serious genital infections, such as necrotizing fasciitis of the perineum. Patients should promptly seek medical attention if they develop symptoms such as pain or tenderness, redness, or swelling of the genitals or the area from the genitals back to the rectum, along with a fever above 100.4°F or malaise.

Jardiance may interact with other medications, such as diuretics, potentially affecting blood pressure and blood sugar levels. Discuss potential interactions with a healthcare provider.

Jardiance is not suitable for individuals with severe or end-stage kidney disease, those on dialysis, or those with known hypersensitivity to empagliflozin. It is also not recommended for use in patients with Type 1 diabetes or diabetic ketoacidosis.

Consult a healthcare provider for personalized advice and to thoroughly discuss any potential risks or concerns before starting Jardiance.