Pertzye (Lipase/Protease/Amylase)

Do’s

• The dosage of Pertzye is determined by your medical condition, diet, weight, and response to treatment. Take this medication as prescribed by your healthcare provider. 
• Pertzye should be taken by mouth with meals and snacks as directed by your healthcare provider.
• Swallow the capsule whole. If you have difficulty swallowing the capsule, you may open it and mix the contents in a small amount of liquid or soft food that does not require chewing, such as room-temperature applesauce. Consult your healthcare provider for specific instructions on what foods or liquids to avoid when mixing. 
• After swallowing the mixture, be sure to drink a glass of water or juice to ensure that all the medication is swallowed. 
• Drink plenty of fluids while taking Pertzye unless otherwise instructed by your healthcare provider.
• If your healthcare provider has recommended a special diet, follow it closely in order to get the most benefit from Pertzye.
• Take Pertzye regularly with every meal or snack to maximize its effectiveness.
• Inform your healthcare provider if your condition does not improve or if it worsens while taking Pertzye.

Don’ts

• Do not exceed the recommended dose. Taking more capsules than prescribed will not improve your condition faster and may increase the risk of side effects.
• Do not crush or chew the capsules or keep them in your mouth, as this can irritate the mouth and affect the medication's effectiveness. 
• Do not mix the capsule’s contents with alkaline food or liquid (such as milk, ice cream, or tea).
• Do not save the medication mixture for later use.
• Do not change brands or dosage forms of pancrelipase (the active ingredient in Pertzye) without consulting your healthcare provider. Stick with the product prescribed to you, as different products may contain different amounts of digestive enzymes.

Common Side Effects: 

• Abdominal pain
• Diarrhea
• Constipation
• Nausea
• Vomiting
• Flatulence

If you experience any of these side effects or any other unusual symptoms, consult your healthcare provider for guidance.

This is not an exhaustive list of side effects, and individual experiences may vary. Consult your healthcare provider or refer to the prescribing information for Pertzye for a comprehensive understanding of potential side effects.

Pertzye may increase the risk of a rare bowel disorder called fibrosing colonopathy. This condition is serious and may require surgery. To reduce the risk, follow the dosing instructions provided by your healthcare provider.

Doses greater than the recommended amount have been associated with colonic strictures, indicative of fibrosing colonopathy, in children with cystic fibrosis. Patients currently receiving higher doses should be examined, and the dosage should be adjusted as necessary.

Discuss with your healthcare provider the potential risks and benefits of taking Pertzye during pregnancy or while breastfeeding.

Pertzye may interact with other medications you are taking. Consult your healthcare provider to determine potential interactions between Pertzye and other drugs.

This is not an exhaustive list of warnings and precautions associated with Pertzye. Consult your healthcare provider or refer to the prescribing information for Pertzye for a comprehensive understanding of potential risks and precautions.