Estraderm Patch (Estradiol)

Do's

• Carefully read the Patient Information Leaflet before using Estraderm and consult your healthcare provider if you have any questions. The patch is typically replaced twice a week (every 3-4 days). Follow your healthcare provider's specific dosing instructions.
• Apply the patch to a clean, dry area of your body as directed. Different brands have different application areas, so confirm with your healthcare provider if unsure.
• Press the patch firmly for 10 seconds to ensure it adheres properly.
• When replacing the patch, choose a different area each time. Wait at least a week before using the same spot again.
• Fold the used patch in half with the sticky side together and throw it away in the trash, away from children and pets. Don't flush it down the toilet. If a patch falls off, reapply it to a different area. If a patch doesn't adhere fully, apply a new one and wear it for the remaining scheduled period. Don't wear two patches at once.
• Use Estraderm regularly as prescribed for optimal benefit. Consider marking your calendar as a reminder for patch changes.
• Tell your healthcare provider if your condition doesn't improve or worsens.

Don'ts

• Don't apply the patch to your breasts, oily, broken, or irritated skin, or areas prone to friction (like your waistline).
• Don't skip reading the information leaflet or disregard your healthcare provider's advice.
• Don't use it in inappropriate areas. Avoid applying the patch to the areas mentioned above (breasts, damaged skin, etc.).

Common side effects:

• Headache
• Hair loss
• Upset stomach or vomiting
• Constipation
• Stomach cramps
• Bloating
• Enlarged or tender breasts
• Vaginal bleeding or spotting
• Painful periods
• Signs of a common cold (e.g., runny nose, throat irritation)
• Weight gain or loss
• Joint pain
• Leg cramps
• Change in sex interest
• Irritation at the application site

Serious side effects (seek medical attention if they occur):

• Vaginal bleeding that is not normal
• Depression or other mood changes
• Memory problems or loss
• Fever
• Difficulty passing urine or changes in urine output
• Painful urination
• Swelling

This is not an exhaustive list, and other side effects may occur. If you experience any unusual or severe side effects while taking an Estraderm patch, contact your healthcare provider for medical advice.

Discuss any allergies to estradiol or other medications before starting the patch.

Tell your healthcare provider about any pre-existing medical conditions, especially:

• Unexplained vaginal bleeding
• Certain cancers (breast, uterus, ovaries)
• Blood clots, stroke, heart disease
• Liver or kidney disease
• Family history of relevant conditions (cancer, blood clots)
• Swelling disorder (angioedema)
• Blood clotting disorders
• High blood pressure, diabetes, cholesterol/triglyceride issues
• Obesity, lupus, thyroid problems, mineral imbalances
• Uterus problems (fibroids, endometriosis)
• Gallbladder disease, asthma, seizures, migraines
• Porphyria (blood disorder)
• Mental/mood disorders (dementia, depression)

Avoid smoking or tobacco use, as it significantly increases risks associated with estrogen therapy.

Discuss upcoming surgery or prolonged bed rest with your healthcare provider, as these can increase blood clot risk. Your healthcare provider might need to adjust your medication.

Inform medical personnel performing MRI scans that you wear the patch. Some patches might contain metals that can cause burns during MRI. Your healthcare provider will advise on proper patch removal and reapplication for the procedure.

This medication might cause skin discoloration. Practice sun protection by limiting sun exposure, avoiding tanning beds/lamps, using sunscreen, and wearing protective clothing.

If you wear contact lenses or are nearsighted, you might experience vision problems. Consult your eye healthcare provider if this occurs.

Children might be more susceptible to side effects, potentially affecting their growth and development. Discuss these risks with your healthcare provider and monitor your child's growth regularly.

This medication is not recommended during pregnancy and may affect breast milk production. Consult your healthcare provider before getting pregnant or breastfeeding.