Airduo Respiclick (Fluticasone/Salmeterol)

Airduo Respiclick

(Brand Option)

Prescription RequiredPrescription Required
FormulationFormulation: Inhalation powder
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(Generic Alternative)

Prescription RequiredPrescription Required
FormulationFormulation: Inhalation powder
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AirDuo RespiClick is a prescription medication indicated for the treatment of asthma in patients aged 12 years and older. It is not used to relieve sudden breathing problems from asthma and should not replace a rescue inhaler. It is a combination product containing two active ingredients: fluticasone and salmeterol.

The combination of fluticasone and salmeterol in AirDuo RespiClick provides both anti-inflammatory and bronchodilator effects, helping to reduce airway inflammation and open up the airways. This can help to prevent asthma symptoms, such as wheezing, shortness of breath, and coughing.


  • Ensure the cap is closed before using the inhaler.
  • Hold the inhaler upright and open the cap completely until it clicks (prepare the dose).
  • Inhale the medication by mouth as directed by your healthcare provider, typically twice daily (around 12 hours apart).
  • Rinse your mouth with water after each use to prevent dryness and irritation. Spit, don't swallow the rinse.
  • Use this medication regularly at evenly spaced times for maximum benefit.
  • Learn the difference between your AirDuo RespiClick (daily controller) and a quick-relief inhaler for sudden breathing problems.
  • Tell your healthcare provider if your condition doesn't improve or worsens.


  • Exhale into the inhaler.
  • Take apart or wash the inhaler or mouthpiece.
  • Open the cap unless you are ready for your next dose.
  • Use other inhalers within 1 minute of using AirDuo RespiClick. (Use AirDuo RespiClick last if using multiple inhalers).
  • Increase your dose or use AirDuo RespiClick more often without consulting your healthcare provider.
  • Use other long-acting beta agonists while on this medication.
  • Stop using your quick-relief inhaler regularly (only use it for sudden breathing problems now). Talk to your healthcare provider for details.
  • Stop taking a different oral corticosteroid unless your healthcare provider instructs you to.
  • Hesitate to tell your healthcare provider if you experience withdrawal symptoms.

It may take a week or longer to experience the full benefit of this medication. Understand what to do in case of worsening symptoms or if your quick-relief inhaler seems less effective.

Common Side Effects of AirDuo RespiClick may include:

  • Headache
  • Throat irritation
  • Hoarseness
  • Cough
  • Sinusitis
  • Upper respiratory tract infection
  • Nausea
  • Vomiting
  • Diarrhea
  • Bronchitis
  • Nasopharyngitis (common cold)
  • Flu-like symptoms
  • Back pain
  • Joint pain
  • Muscle pain

Serious side effects of AirDuo RespiClick

  • Sudden breathing problems immediately after inhaling the medication
  • Serious allergic reactions, such as rash, hives, swelling, or difficulty breathing
  • Eye problems, including glaucoma and cataracts (regular eye exams are recommended while using AirDuo RespiClick)
  • Acute respiratory events, including fatalities, in patients with significantly worsening or acutely deteriorating asthma
  • Systemic eosinophilic conditions in rare cases

This is not an exhaustive list, and other side effects may occur. If you experience any unusual or severe side effects while taking  Airduo respiclick,  contact your healthcare provider for medical advice.

Disclose your medical history to your healthcare provider, especially:

  • Current/past infections (tuberculosis, herpes)
  • Heart problems (high blood pressure, chest pain, irregular heartbeat): Other health conditions (bone loss, thyroid issues, diabetes, eye problems, seizures, liver disease)

AirDuo RespiClick may cause irregular heartbeat (QT prolongation) which can be serious (fast/irregular heartbeat, dizziness, fainting).

This risk increases with certain medical conditions or medications. Tell your healthcare provider about any relevant conditions or medications you take.

AirDuo RespiClick may mask infection symptoms and increase your susceptibility to infections.

Avoid people with contagious illnesses (chickenpox, COVID-19, measles, flu). Consult your healthcare provider if exposed to an infection.

If you recently stopped oral corticosteroids, your body might respond poorly to stress. Inform your healthcare provider before surgery, emergencies, or serious illness/injury.

Disclose all medications (prescription, non-prescription, herbal) to your healthcare provider before surgery.

Increased risk of pneumonia and higher sensitivity to side effects (QT prolongation).

Long-term use may slow growth (regular healthcare provider visits recommended).

Use only when clearly necessary. Consult your healthcare provider about risks and benefits.

Brand Name:

Airduo Respiclick

Generic name:

Fluticasone/Salmeterol, Fluticasone/Salmeterol

Other Names:

Fluticasone Propionate and Salmeterol Inhalation Powder, Airduo Respiclick

Strength(s): 55/14mcg, 113/14mcg, 232/14mcg
Quantities Available: 60, 120, 180

Inhalation powder

Important Information
The information above for Airduo Respiclick (Fluticasone/Salmeterol) was provided to by third parties. In no way should this information substitute for the advice of a physician. Consult a doctor or qualified health care professional if you have any medical concerns. widget logo
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