Lioresal DS (Baclofen)

Do’s

• Take it exactly as prescribed by your healthcare provider, with or without food.
• Start with a low dose and increase gradually as directed by your healthcare provider.
• Use a special measuring device for the liquid form (not a household spoon).
• Shake the liquid suspension well before each dose.
• For granules:
  • Shake the packet before use.
  • Empty the entire contents into your mouth and swallow.
  • Drink water if needed afterwards.
  • Mix with soft food/liquid (1 tablespoonful) if preferred, take within 2 hours of mixing.
• Take it regularly at the same times each day.
• Talk to your healthcare provider before stopping this medication.
• Tell your healthcare provider if your condition worsens.

Don'ts

• Don't increase your dose or take it more often than prescribed.
• Don't abruptly stop taking this medication.
• Don't use expired medication.

Common side effects:

• Nausea
• Drowsiness
• Dizziness
• Weakness
• Fatigue
• Headache
• Constipation
• Dry mouth

Serious side effects may include:

• Mental/mood changes (such as confusion, depression, hallucinations)
• Allergic reactions (rash, itching/swelling, severe dizziness, trouble breathing)
• Serious problems from sudden withdrawal of the medication (high fever, mental changes, more spasms, muscle stiffness, very bad muscle problems, organ problems, and death)
• Interactions with other medications that may increase the risk of serious side effects

This is not an exhaustive list, and other side effects may occur. If you experience any unusual or severe side effects while taking Lioresal DS, contact your healthcare provider for medical advice.

Talk to your healthcare provider before taking Lioresal DS if you have any allergies, especially to Baclofen itself or any inactive ingredients.

Inform your healthcare provider of your medical history, particularly if you have:

• Kidney disease
• Mental/mood disorders (like schizophrenia)
• Brain disorders (like seizures or stroke)

Lioresal DS may cause dizziness or drowsiness. Avoid driving, operating machinery, or activities requiring alertness until you know how it affects you.

Alcohol and marijuana (cannabis) can worsen dizziness or drowsiness caused by Lioresal DS. It's best to avoid them while taking this medication.

Tell your healthcare provider about all medications you take (prescription, non-prescription, and herbal) before any surgery.

Older adults may be more sensitive to side effects, especially drowsiness and mental/mood changes.

Pregnant women should only use Lioresal DS when clearly necessary. Discuss risks and benefits with your healthcare provider.

Lioresal DS passes into breast milk. Consult your healthcare provider before breastfeeding.