Hiprex (Methenamine Hippurate)


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FormulationFormulation: Tablet
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$84.00 ($0.84 per tablet)

Methenamine Hippurate

(Generic Alternative)

Prescription RequiredPrescription Required

This generic medication is not available at the moment.

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Hiprex (Methenamine) is a medication indicated to prevent or manage recurring urinary tract infections (UTIs) caused by certain bacterial strains. It cannot treat an active UTI. You'll need antibiotics to clear an existing infection.

Hiprex targets and stops the growth of bacteria specifically within the urinary tract. It contains an ingredient that increases the acidity of your urine. This acidic environment is needed for methenamine to transform into formaldehyde, which has antibacterial properties.

Methenamine works exclusively against bacterial UTIs. It won't help with other bacterial infections in the body or viral infections like colds or the flu. Unnecessary or excessive use of Hiprex (or any antibacterial drug) can make it less effective over time.


  • Take Methenamine at evenly spaced times each day, ideally at the same time(s) every day as this helps maintain consistent medication levels in your body. 
  • Follow your healthcare provider's instructions for dosage. 
  • Inform your healthcare provider if you experience any returning symptoms of a urinary tract infection, such as burning, painful, or frequent urination. 


  • Don't adjust the dosage or frequency of medication without consulting your healthcare provider. 

Methenamine dosage is determined by several factors including the brand, your medical condition, age, and weight. Methenamine works best in acidic urine. Your healthcare provider might check your urine pH and recommend ways to increase acidity, like taking vitamin C, limiting certain foods (milk products, most fruits), or adjusting medications.  

Common Side Effects:

  • Painful urination
  • Nausea
  • Upset stomach
  • Difficulty urinating
  • Rash

Serious Side Effects

  • Increased urination
  • Painful urination
  • Blood in your urine
  • Swelling
  • Shortness of breath

This is not an exhaustive list, and other side effects may occur. If you experience any unusual or severe side effects while taking  Hiprex,  contact your healthcare provider for medical advice.

Inform your healthcare provider of any allergies to methenamine, formaldehyde, or any other ingredients in Hiprex.

Discuss your medical history with your  healthcare provider, especially if you have:

  •       Kidney problems
  •       Liver problems
  •       Dehydration

Before undergoing surgery, tell your healthcare provider or dentist about all medications you use, including Hiprex and any other prescription, over-the-counter, or herbal products.

Hiprex should only be used during pregnancy if clearly necessary. Discuss the risks and benefits with your healthcare provider.

Hiprex passes into breast milk and its effects on a nursing infant are unknown. Consult your healthcare provider before breastfeeding while taking this medication.

Brand Name:


Generic name:

Methenamine Hippurate

Other Names:


Strength(s): 1g
Quantities Available: 100


Important Information
The information above for Hiprex (Methenamine Hippurate) was provided to DoctorSolve.com by third parties. In no way should this information substitute for the advice of a physician. Consult a doctor or qualified health care professional if you have any medical concerns.
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