Xadago (Safinamide Methansulfonate)

Do’s

• Take Xadago exactly as prescribed by your healthcare provider, typically once daily with or without food.
• Take it consistently at the same time each day to maximize its effectiveness.
• Follow your healthcare provider's instructions regarding dosage and duration of treatment. Don't adjust your dose or take it more often than prescribed.
• Inform your healthcare provider about all medications you take, including prescriptions, over-the-counter drugs, vitamins, and herbal products. This helps avoid potential interactions.
• Report any side effects you experience to your healthcare provider.
• Tell your healthcare provider if your condition worsens or if Xadago seems to be less effective.

Don'ts

• Don't stop taking Xadago abruptly. Your healthcare provider may need to gradually decrease your dose to avoid worsening your condition.
• Don't consume large amounts of tyramine-rich foods while taking Xadago and for 2 weeks after stopping it. Consult your healthcare provider for a list of foods to avoid.
• Don't take Xadago if you are allergic to safinamide or any other ingredient in the medication.

Common Side Effects:

• Dyskinesia: Uncontrolled and sudden body movements.
• Hypertension: High blood pressure.
• Increased serum alanine aminotransferase: An enzyme found in the liver, and increased levels may indicate liver damage.
• Mild burning or tingling after applying the medicine
• Skin dryness or flaking
• Swelling
• Skin redness or discoloration
• Problems related to sleep

Serious Side Effects:

• Allergic Reaction: Signs of an allergic reaction may include hives, difficult breathing, and swelling of the face, lips, tongue, or throat.
• Serotonin Syndrome
• Confusion
• Excess sweating
• Blood pressure changes
• Muscle spasms or stiffness
• Diarrhea
• Very high fever.
• Withdrawal Effects
• Very serious high blood pressure reaction

This is not an exhaustive list, and other side effects may occur. If you experience any unusual or severe side effects while taking Xadago,  contact your healthcare provider for medical advice.

Inform your healthcare provider if you are allergic to safinamide or any ingredients in Xadago.

Disclose any pre-existing medical conditions to your healthcare provider before using Xadago, especially:

• Liver disease
• High blood pressure
• Mental/mood disorders (schizophrenia, bipolar disorder, depression)
• Eye problems (macular degeneration, uveitis)
• Sleep disorders

Xadago may cause drowsiness or dizziness. Avoid driving, operating machinery, or activities requiring alertness until you are sure you can do them safely. Limit alcohol and marijuana use while taking Xadago.

Tell your healthcare provider about all medications you take, including Xadago, before having surgery.

Xadago should only be used during pregnancy when clearly necessary. Discuss the risks and benefits with your healthcare provider.

It is unknown if Xadago passes into breast milk. Consult your healthcare provider before breastfeeding.