About Ongentys (Opicapone)
Ongentys (Opicapone) is a catechol-o-methyltransferase (COMT) inhibitor used to treat Parkinson’s disease. Dopamine is a natural substance that is needed for normal brain function. It helps to control movement, motivation, and attention. People with Parkinson’s disease have low levels of dopamine in their brains.
The main ingredient of Ongentys is Opicapone. Opicapone is a catechol-o-methyltransferase (COMT) inhibitor. COMT is an enzyme that breaks down dopamine. COMT plays a role in the breakdown of neurotransmitters such as dopamine, adrenaline, and norepinephrine. Dopamine is a neurotransmitter that helps control movement, emotion, and behavior. Opicapone increases the amount of dopamine in the brain. This can improve symptoms of Parkinson’s disease, such as stiffness, tremors, and walking problems. Opicapone can also help relieve “OFF” periods during the day when Parkinson’s symptoms worsen.
Uses of Ongentys (Opicapone)
- Take Ongentys exactly as your doctor has instructed. Read all drug guides or instruction sheets and follow all guidelines on your prescription label.
- When you start or stop taking Ongentys, your doctor may need to alter the doses of any other Parkinson’s disease medications you are taking.
- Ongentys are commonly taken before going to bed. Pay close attention to your doctor’s dosing instructions.
- Ongentys should be taken on an empty stomach. Do not consume anything for at least 1 hour before or after taking this medication.
- Your blood pressure may need to be tested regularly.
- Ongentys may cause you to fall asleep while working, talking, eating, or driving during the day. Even if you are awake, you may fall asleep unexpectedly. Inform your doctor if you have daytime tiredness or drowsiness.
- Change your doses or discontinue any medications without consulting your doctor. Inform your doctor if any of your medications appear to be failing.
- Store away from moisture and heat at room temperature.
Warnings and Dosage
Interactions and Warnings Of Ongentys (Opicapone)
Taking Ongentys with other sleepy medicines can exacerbate this effect.
Before using an opioid, sleeping pill, muscle relaxer, or drug for anxiety or seizures, consult your doctor.
Inform your doctor about all of your other medications, particularly if you’re taking any of the following: Dobutamine, Dopamine, Epinephrine, or Norepinephrine and Isoproterenol.
Other pharmaceuticals, including prescription and over-the-counter medications, vitamins, and herbal supplements, may interact with Opicapone. This list does not include all probable medication interactions.
Ongentys should not be used if you are allergic to Opicapone or if you have a tumor that secretes hormones, such as:
- pheochromocytoma (adrenal gland tumor);
- paraganglioma (tumor of the nerve cells) (tumor of the nerve cells).
To ensure that Ongentys is suitable for you, inform your doctor if you have ever had the following list below:
- a sleep disorder that causes drowsiness during the day;
- narcolepsy or other illnesses that cause drowsiness suddenly;
- muscular motions that are uncontrollable;
- uncommon and powerful impulses to act (for example, gambling, binge eating, or compulsive buying);
- Insanity, hallucinations, or psychosis;
- liver illness;
- renal failure;
- If you are pregnant or breastfeeding, inform your doctor.
Side Effects of Ongentys (Opicapone)
If you have hives, difficulty breathing, or swelling of your face, lips, tongue, or throat as a result of an allergic response to Ongentys, get emergency medical attention. If you have any of the following symptoms below, contact your doctor right away.
- A light-headed sensation, as if you might pass out;
- confusion, hallucinations (hearing or seeing things that are not present);
- anger, violence, odd thoughts, or conduct;
- uncontrollable facial muscle movements (chewing, lip smacking, frowning, tongue movement, blinking, or eye movement);
- tremors, stiffness, or muscle spasms.
While using this medication, you may experience heightened sexual cravings, unexpected gambling urges, or other extreme urges.
If any of the below happens, consult your doctor: experiencing dizziness, a muscular activity that is uncontrollable, abnormal blood tests, or constipation.
When you stop using Ongentys, look out for withdrawal symptoms such as tight muscles, high fever, sweating, confusion, fast or irregular heartbeats, tremors, or dizziness. For medical advice on side effects, contact your doctor.
Frequently Asked Questions about Ongentys (Opicapone)
When is the most appropriate time to take Ongentys?
Ongentys (Opicapone) should be taken once daily at bedtime and at least one hour after eating. Eating is also not advised for an hour after taking Ongentys.
Why is Ongentys administered at night?
Ongentys increases the quantity of levodopa that reaches the brain, extending its duration of action. Ongentys accomplishes this by inhibiting the COMT enzyme, which degrades levodopa in the blood. The quantity of levodopa available after a dose is increased by taking Ongentys at night or at least one hour apart from levodopa. However, any interaction between the two medications during the levodopa absorption phase is avoided.
When Ongentys is taken at night, there is more freedom to change when levodopa is given during the day, as there is no need to consider potential absorption interactions.
How long does Ongentys take to work?
Ongentys begins to work within one week after beginning treatment. Ongentys has a full effect within two to three weeks of starting medication.
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Ongentys (Opicapone) Price
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The information above for Ongentys (Opicapone) was provided to DoctorSolve.com by third parties. In no way should this information substitute for the advice of a physician. Consult a doctor or qualified health care professional if you have any medical concerns.