Boniva Injection (Ibandronate sodium)

Do’s

• Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before starting to use Boniva Injection and each time you receive another dose. If you have any questions, ask your healthcare provider for clarification.
• Boniva Injection is given by a healthcare provider once every 3 months. It is administered by injection into a vein over a period of 15-30 seconds.
• Use this medication regularly to get the most benefit from it, even if you feel well.
• Most people with osteoporosis do not have symptoms, so it's crucial to remember to receive the injection every 3 months. It may be helpful to mark your calendar with a reminder to ensure timely administration of the medication.
• Continue taking other medications for your condition as directed by your healthcare provider.
• Remember to keep all appointments with your healthcare provider and follow their instructions carefully to ensure the safe and effective use of Boniva Injection.

Common Side Effects:

• Bone, muscle, and joint pains
• Flu-like symptoms
• Headache
• Heartburn
• Stomach pain
• Diarrhea
• Back pain
• Pain in the extremities
• Redness or swelling around the injection site

Most of the common side effects of Boniva Injection are temporary, lasting a few days to weeks.

Flu-like symptoms generally disappear after 24-48 hours and usually occur only after the first injection.

Long-Term Side Effects:

• Severe allergic reactions
• Severe kidney problems
• Severe jaw bone problems (osteonecrosis)
• Unusual thigh bone fractures
• Low calcium levels in the blood (hypocalcemia) 

If you experience side effects that seem long term, become bothersome, or severe, talk with your healthcare provider.

Remember to consult your healthcare provider for personalized advice and guidance regarding the potential side effects of Boniva Injection. If you have specific concerns about the side effects or need further information, seek professional medical advice.

Overdosage with intravenous bisphosphonates, including Boniva, may result in hypocalcemia, hypophosphatemia, and hypomagnesemia. Clinically relevant reductions in serum levels of calcium, phosphorus, and magnesium should be corrected by intravenous administration of specific substances.

Boniva is contraindicated in patients with hypocalcemia and those with known hypersensitivity to Boniva Injection or any of its excipients. Cases of anaphylaxis, including fatal events, have been reported.

Boniva Injection must be administered intravenously only by a healthcare provider. Care must be taken not to administer intra-arterially or paravenously as this could lead to tissue damage. Appropriate medical support and monitoring measures should be readily available when Boniva Injection is administered.

If anaphylactic or other severe hypersensitivity/allergic reactions occur, immediate discontinuation of the injection and initiation of appropriate treatment is necessary.

Boniva Injection may interact with other medications. Discuss all current medications with your healthcare provider before starting treatment.

Boniva Injection may cause a decrease in serum calcium values. Treatment of hypocalcemia, hypovitaminosis D, and other disturbances of bone and mineral metabolism should be addressed before starting Boniva Injection therapy.

Adequate intake of calcium and vitamin D is important in all patients. Patients should receive supplemental calcium and vitamin D if dietary intake is inadequate.

Consult with your healthcare provider for personalized advice and guidance regarding the use of Boniva Injection. If you have specific concerns about the warnings and precautions or need further information, seek professional medical advice.