Prilosec (Omeprazole)


(Brand Option)

Prescription RequiredPrescription Required
FormulationFormulation: Capsule, capsule
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$184.37 ($2.05 per capsule)

$155.50 ($1.73 per capsule)

$205.00 ($2.28 per capsule)


(Generic Alternative)

Prescription RequiredPrescription Required
FormulationFormulation: Capsule
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$80.00 ($0.89 per capsule)

$31.00 ($1.11 per capsule)

$63.00 ($0.75 per capsule)

$59.00 ($0.70 per capsule)

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Prilosec (omeprazole) is indicated for the following conditions:
  • Short-term Treatment of Active Duodenal Ulcer: Prilosec is indicated for the short-term treatment of active duodenal ulcer in adults. Most patients heal within four weeks, and some patients may require an additional four weeks of therapy.
  • Eradication of H. pylori Infection and Duodenal Ulcer Disease: Prilosec, in combination with clarithromycin and amoxicillin, is indicated for the treatment of patients with H. pylori infection and duodenal ulcer disease (active or up to 1-year history) to eradicate H. pylori in adults.
  • Erosive Esophagitis (EE) due to Acid-Mediated Gastroesophageal Reflux Disease (GERD): Prilosec is indicated for the short-term treatment (4 to 8 weeks) of EE due to acid-mediated GERD that has been diagnosed by endoscopy in patients 1 year of age and older. It is also indicated for the maintenance healing of EE due to acid-mediated GERD in patients 1 year of age and older.
  • Pediatric Patients 1 Month to Less Than 1 Year of Age: Prilosec is indicated for the short-term treatment (up to 6 weeks) of EE due to acid-mediated GERD in pediatric patients 1 month to less than 1 year of age.
  • Before starting to take Prilosec and each time you get a refill, read the Medication Guide provided by your pharmacist. If you have any questions, ask your healthcare provider for clarification.
  • Prilosec is usually taken by mouth before a meal, as directed by your healthcare provider, usually once daily. The dosage and length of treatment are based on your medical condition and response to treatment. In children, the dosage is also based on weight.
  • If taking the medication by mouth, the contents of a packet should be emptied into a container with a specific amount of water, as per the manufacturer package directions, and then stirred well. The mixture should be consumed within a specific time frame, and any remaining medication in the container should be handled as per instructions. If giving the medication through a nasogastric or gastric tube, detailed instructions should be obtained from a healthcare provider.
  • If taking Prilosec tablets, the tablets should be swallowed whole and should not be crushed, chewed, or opened.
  • Use this medication regularly to get the most benefit from it. To help remember, take it at the same time each day. Continue taking this medication for the prescribed length of treatment even if feeling better.
  • Inform your healthcare provider if your condition lasts or gets worse, and seek guidance on the duration of treatment.
  • If needed, antacids may be taken along with this medication. If also taking sucralfate, it's recommended to take Prilosec at least 30 minutes before sucralfate.
Common Side Effects:
  • Headache
  • Stomach pain
  • Nausea
  • Vomiting
  • Diarrhea
  • Gas
  • Cold symptoms such as stuffy nose, sneezing, and sore throat, especially in children, may also occur
  Serious Side Effects: 
  • Symptoms of a low magnesium blood level, such as muscle spasms, irregular heartbeat, and seizures
  • Signs of lupus, such as a rash on the nose and cheeks, and new or worsening joint pain
If serious side effects occur, they should be reported to a healthcare provider right away. Long-term use of Prilosec has been linked to kidney damage, bone fractures, vitamin B-12 deficiency, and magnesium deficiencies. Overusing Prilosec for longer than 3 years could lead to a vitamin B-12 deficiency. Rarely, serious side effects such as liver and kidney damage, and an increased risk of fractures, may occur. Ask a healthcare provider about Prilosec side effects before taking it.

Consult a healthcare provider before taking Prilosec to ensure there are no potential interactions with other medications being taken.

Patients should inform their healthcare provider if they are urinating less than usual, or if they have blood in their urine, as Prilosec OTC can cause kidney problems.

Diarrhea may be a sign of a new infection, and patients should call their healthcare provider if they have diarrhea that is watery or has blood in it. Prilosec OTC may cause new or worsening symptoms of lupus, and patients should inform their healthcare provider if they have joint pain and a skin rash on their cheeks or arms that worsens in sunlight.

This is not an exhaustive list of warnings and precautions. Consult a healthcare provider for personalized advice and guidance.


Brand Name:


Generic name:

Omeprazole, Omeprazole

Other Names:

Losec, Omeprazole, Omez

Strength(s): 10mg, 20mg, 40mg
Quantities Available: 28, 84, 90

Capsule, capsule

Important Information
The information above for Prilosec (Omeprazole) was provided to by third parties. In no way should this information substitute for the advice of a physician. Consult a doctor or qualified health care professional if you have any medical concerns. widget logo
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