Stalevo 200 (Carbidopa/levodopa/entacapone)

Do’s

• The dosage of Stalevo 200 is determined by your healthcare provider based on your medical condition and response to treatment. Take the medication regularly to receive the maximum benefit from it. 
• Stalevo 200 should be taken by mouth with or without food, as directed by your healthcare provider. It is typically taken 3 to 4 times a day, with one tablet per dose. Swallow the tablet whole.
• Taking Stalevo 200 with food can help decrease nausea. However, it is advisable to avoid a high-protein diet as it may reduce the absorption of levodopa. Additionally, taking the medication with a high-fat, high-calorie meal can delay its onset of action by about 2 hours.
• Separate the dose of Stalevo 200 by as many hours as possible from any iron supplements or products containing iron, such as multivitamins with minerals. Iron can interfere with the absorption of this medication.
• Some patients may experience a "wearing-off" effect before the next dose is due, where symptoms worsen. An "on-off" effect, characterized by sudden short periods of stiffness, can also occur. If these effects happen, contact your healthcare provider for possible dose adjustments that may alleviate this effect.
• If your symptoms do not improve or worsen, notify your healthcare provider for further evaluation and guidance.

Don’ts

• Do not alter the prescribed dosage without consulting your healthcare provider.
• Do not crush, chew, or split the tablet. These actions can result in an incorrect dose and may also cause staining of the mouth, dentures, and saliva.
• Do not stop taking Stalevo 200 without consulting your healthcare provider. Abruptly stopping the medication can worsen certain conditions and may lead to withdrawal symptoms, such as anxiety, depression, confusion, fever, and muscle stiffness. To prevent withdrawal symptoms, your healthcare provider may gradually reduce your dose if discontinuation is necessary. 

Common Side Effects:

• Diarrhea
• Dyskinesia (hyperkinetic muscle activity)
• Nausea
• Dark urine
• Urine discoloration
• Abdominal pain
• Vomiting

This is not an exhaustive list of side effects, and other side effects may occur. Some side effects may be more common at the beginning of treatment and may improve as treatment continues. Consult with your healthcare provider if you have any concerns or questions about the side effects you may experience.

If you experience any serious side effects or have concerns about your medication, contact your healthcare provider immediately for further evaluation and guidance.

Stalevo 200 may interact with other medications you are taking. Inform your healthcare provider about all the medications you are currently using to avoid potential interactions. 

The risk of increased sleepiness associated with Stalevo 200 can be further increased by using alcohol or other medications that can make you drowsy. Avoid driving or engaging in other potentially dangerous activities if you experience increased sleepiness. Consult your healthcare provider for further guidance.

If you are undergoing surgery or need to undergo laboratory tests, inform your healthcare provider that you are taking Stalevo 200. They may provide specific instructions or adjustments to your medication regimen.

This is not an exhaustive list of warnings and precautions associated with Stalevo 200. Discuss your medical history, current medications, and any concerns with your healthcare provider for personalized advice.