Zarontin (Ethosuximide)

Do’s

• Before starting Zarontin, read the Medication Guide provided by your pharmacist. If you have any questions, ask your healthcare provider.
• Zarontin is taken by mouth with or without food as directed by your healthcare provider, usually once or twice daily.
• If you are using the liquid form of Zarontin, carefully measure the dose using a special measuring device/spoon. 
• The dosage of Zarontin is based on your age, medical condition, blood levels of ethosuximide, and response to treatment. For children, the dosage may also be based on their weight.
• Follow your healthcare provider's dosing instructions exactly. They will typically start you on a low dose and then slowly increase your dose. It may take several weeks or months to reach the best dose for you and to get the full benefit from this medication.
• Use Zarontin regularly at the same time(s) each day to get the most benefit from it. This will also help you remember to take it consistently.
• If your condition does not improve or if it worsens, inform your healthcare provider.

Don’ts

• Avoid using a household spoon when measuring the liquid form, as it may not provide the correct dose.
• Do not stop taking Zarontin without consulting your healthcare provider. Some conditions may worsen when the drug is suddenly stopped. Your dose may need to be gradually decreased.

Common Side Effects: 

• Drowsiness
• Dizziness
• Headache
• Nausea
• Vomiting
• Loss of appetite 

Serious Side Effects: 

• Allergic reactions such as skin rash, hives, sores in the mouth, and blistering or peeling skin. 
• Mental or mood problems, such as depression, suicidal thoughts/attempts, or other mental/mood problems. 

Seek immediate medical attention if symptoms of allergic reaction occur. Additionally, inform your healthcare provider immediately if you notice unusual or sudden changes in mood, thoughts, or behavior.

This is not an exhaustive list of side effects, and individuals may experience different reactions to the medication. If you have concerns about the potential side effects of Zarontin, consult with your healthcare provider for personalized advice and guidance.

Do not start or stop taking Zarontin without your healthcare provider's advice, and inform your healthcare provider immediately if you become pregnant. Zarontin may cause harm to an unborn baby, but having a seizure during pregnancy could harm both mother and baby. The benefit of preventing seizures may outweigh any risks to the baby.

In some cases, Zarontin may affect platelet count. If drug-induced immune thrombocytopenia (DITP) is suspected, discontinue Zarontin, monitor serial platelet counts, and treat as appropriate. Avoid future use of Zarontin in patients with a history of ethosuximide-induced DITP.

Antiepileptic drugs, including Zarontin, may increase the risk of suicidal thoughts or behavior. Patients taking these drugs should be monitored for the emergence or worsening of depression, suicidal thoughts or behavior, and any unusual changes in mood or behavior.

Zarontin capsules should be stored at room temperature, between 59°F to 86°F (15°C to 30°C), while Zarontin syrup (oral solution) should be preserved in tight containers at 68-77°F (20-25°C). Protect Zarontin from freezing and light and keep it out of the reach of children.

Zarontin should only be used for the condition for which it was prescribed. It should not be given to other people, even if they have the same condition, as it may harm them. If more information is needed, consulting a healthcare provider is recommended.

If a dose of Zarontin is missed, it should be taken as soon as remembered. However, if it is almost time for the next dose, delaying that dose for a few hours is advised. Consult your healthcare provider for more advice if unsure about what to do.