Generic Name: carbidopa, levodopa, and entacapone
Drug Class: aromatic amino acid / aromatic amino acid decarboxylation inhibitor / catechol-O-methyltransferase (COMT) inhibitor / anti-parkinson agent
Stalevo 125 Indications
Stalevo 125 is an oral prescription drug used to treat Parkinson’s disease (PD). It is used by patients who previously took carbidopa/levodopa and entacapone as individual products. It is used to replace carbidopa/levodopa, without entacapone, among patients experiencing end-of-dose “wearing-off.” It also helps relieve PD symptoms, such as shakiness, muscle stiffness, spasms, difficulty moving, and poor muscle control.
Warnings & Dosage
Stalevo 125 Warnings and Precautions
Do not take this oral prescription drug if you have a known allergy to carbidopa, levodopa, entacapone, or any Stalevo 125 ingredients the tablet may contain. Always watch for any signs of serious allergic reactions when you are on this drug, including trouble breathing, swelling of the face and neck, swollen lymph nodes, severe dizziness, hives/itchiness, and skin rashes. If this occurs, stop taking this oral medication and seek emergency medical help immediately.
This medication may be contraindicated for people with a history of asthma, breathing problems, heart disease, kidney disease, blood disorders, gastrointestinal ulcers, glaucoma, sleep disorders, seizures, and mental or mood disorders. Additionally, because of possible drug interactions, you should discuss all the prescription medications, OTC medications, supplements, and herbal products you are taking.
Dizziness, lightheadedness, and drowsiness are among the common adverse reactions to this oral medication. Practice safety caution when doing tasks that would need alertness, most especially driving. You must also limit your alcohol intake.
Pregnant and breastfeeding moms must take this oral drug only if extremely necessary. It is unknown if it can cause harm to unborn
babies and breastfed infants. Discuss all the possible risks with your doctor before you decide to take this product.
Stalevo 125 Dosage Forms
Stalevo 125 is available in 31.25 mg/125 mg/200 mg tablets. This is usually prescribed three to four times a day or as directed by the doctor.
Stalevo 125 Mechanism of Action
Its carbidopa component works by inhibiting the decarboxylation of peripheral levodopa, which leads to having more levodopa available for transport to the brain. It is also rapidly decarboxylated to dopamine which increases dopamine levels. Levodopa also acts as a metabolic precursor of dopamine, which also contributes to the increase of the monoamine neurotransmitter’s level.
Entacapone contributes to the action as it inhibits the catechol-O-methyl transferase (COMT). When administered with carbidopa and levodopa, it stops the destruction of nerve cells caused by Parkinson’s disease.
How to Take Stalevo 125
Before taking Stalevo 125, it is important to read the patient information leaflet or the medication guide given by a healthcare professional. You must not take this or other drugs unless you fully understand the uses and directions. Check with your physician or pharmacist for further medical advice or additional information.
This anti-Parkinson tablet is only meant to be taken by mouth. It is best to take this oral drug with a meal to avoid nausea. Do not eat high-protein foods because they can decrease the absorption of levodopa. You should also avoid high-fat and high-calorie meals because they can delay the action of this medication. Swallow the oral tablet and drink water after. Do not split, chew, or crush the product because doing so can stain your dentures, mouth, and saliva.
Make a dosing schedule. If you are taking iron supplements or any product that contains iron, administer them separately as far as possible because iron can also decrease the absorption of Stalevo. Do not increase or decrease your Stalevo 125 dosage. You should not also take this oral medication more frequently than advised. Further, never discontinue abruptly because doing so may result in worsening of Parkinson’s symptoms.
Stalevo 125 Side Effects
Mild & Common Side Effects:
- Dry mouth
- Loss of appetite
- Stomach upset
- Trouble sleeping
- Dark saliva, urine, or sweat
Severe Side Effects:
- Suddenly falling asleep
- Worsening spasms
- Increased eye blinking or twitching
- Persistent diarrhea
- Severe abdominal pain
- Black, tarry stool
- Muscle pain
- Muscle weakness
- Increased signs of rigidity of your body
- Changes in urine output
- Persistent sore throat
- Easy bruising or bleeding
- Unusual fatigue
- Unusual strong urges
- Chest pain
- Tingling of the hands or feet
- Mental or mood changes
- Severe confusion
- Irregular heartbeat
- Neuroleptic malignant syndrome
Note that this is not a complete/full list of the side effects of Stalevo 125.
If you experience severe/persistent adverse reactions, discontinue this medication and talk to your doctor or health care professional.
Frequently Asked Questions (FAQs)
How much does Stalevo 125 cost in Canada?
Get the best deals when you buy your Stalevo 125 prescription from DoctorSolve.
We provide the lowest prices of prescription drugs for our patients. For more information regarding the Stalevo 125 price in Canada, check the top of this page.
What is Stalevo 125 used for?
Stalevo 125 is being used to treat a certain central nervous system degenerative disorder called Parkinson’s disease. It helps manage muscle rigidity, slowed movement, and signs of resting tremors.
What is the difference between Sinemet and Stalevo?
Sinemet is also a prescription drug used to treat symptoms of Parkinson’s disease. While Stalevo contains carbidopa, levodopa, and entacapone, Sinemet only has carbidopa and levodopa.
Does Stalevo 125 affect blood pressure?
This medication can affect blood pressure. Some patients report low blood pressure or hypotension while on this therapy. You should always look out for signs of hypotension and limit alcohol consumption because alcohol can also trigger hypotension.
What happens when you stop taking Stalevo 125?
When you discontinue this antiparkinsonian agent abruptly, and without the advice of your doctor, you may experience worsening symptoms of Parkinson’s disease. You should keep using this drug until the doctor prescribes it.
How often should Stalevo 125 be taken?
It will depend on how severe the symptoms or condition is. However, the maximum dosage for Stalevo 125 is 8 tablets every 24 hours. Do not take this oral drug more frequently than prescribed.
Where can I buy Stalevo 125?
You can buy Stalevo 125 from our online pharmacy. You will be required to send a valid prescription from your doctor to dispense this drug.
The information above for Stalevo 125 (Carbidopa/levodopa/entacapone) was provided to DoctorSolve.com by third parties. In no way should this information substitute for the advice of a physician. Consult a doctor or qualified health care professional if you have any medical concerns.