Baraclude is a new antiviral prescription drug used for chronic infection with the hepatitis B virus (HBV) in adults who also have active liver damage.

What is Hepatitis B?

Hepatitis B is a disease of the liver caused by the Hepatitis z virus (HBV), a member of the Hepadnavirus family and one of several unrelated viral species which cause viral hepatitis. Symptoms of the acute illness caused by the virus include liver inflammation, vomiting, jaundice, and rarely, death. Chronic hepatitis B may cause liver cirrhosis which may then lead to liver cancer.

Hepatitis B is largely transmitted through exposure to bodily fluids containing the virus. This includes unprotected sexual contact, blood transfusions, re-use of contaminated needles and syringes, vertical transmission from mother to child during childbirth, and so on.

What should I know about Baraclude before using it?

• Lactic acidosis and severe liver problems, including fatal cases, have been reported with the use of Baraclude, alone or in combination. Contact your physician immediately if you experience nausea, vomiting, or unusual or unexpected stomach discomfort; weakness and tiredness; shortness of breath; weakness in the arms and legs; yellowing of the skin or eyes; or pain in the upper stomach area. These may be early symptoms of lactic acidosis or liver problems.
  
  
• Some people who have taken medicines like Baraclude have developed serious liver problems called hepatotoxicity, with liver enlargement (hepatomegaly) and fat in the liver (steatosis). Call your healthcare provider right away if; your skin or the white part of your eyes turns yellow (jaundice), your urine turns dark, your bowel movements (stools) turn light in color, you don't feel like eating food for several days or longer, you feel sick to your stomach (nausea) or if you have lower stomach pain. These may be early symptoms of liver problems.
  
  
• Follow your physician's instructions with respect to high-risk activities such as unprotected sex and the sharing of needles. Baraclude does not reduce the risk of passing hepatitis B virus to others.
  
  
• It is not known whether Baraclude passes into breast milk and what effect it may have on a nursing baby. Do not take Baraclude without first talking to your doctor if you are breast-feeding a baby.

How do I take Baraclude?

Baraclude is available as 0.5mg tablets and 1mg tablets and should be taken with a full glass of water on an empty stomach - at least 2 hours after a meal and at least two hours before the next meal. Try to take it at the same time every day.

Your dose depends on whether you have been treated for hepatitis B virus infection before and what medicine you took. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Store Baraclude at room temperature away from moisture and heat.

Does Baraclude have any side effects?

There are less serious side effects which may likely occur. Continue taking Baraclude and talk to your doctor if you experience:

• fatigue or tiredness;
  
• mild nausea, vomiting, diarrhea, or decreased appetite;
  
• headache;
  
• dizziness;
  
• skin rash; or
  
• insomnia

If you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives), stop taking Baraclude and seek emergency medical attention.

DoctorSolve Healthcare Solutions Inc., a Canadian Internet-based pharmacy intermediary (license #BC Q37),offers lower cost, long-term prescription drugs. A professionally registered pharmacist fills all prescriptions. A certified member of the Canadian International Pharmacy Association, DoctorSolve is ranked as one of the best Canadian pharmacies online by PharmacyChecker.com. DoctorSolve has filled more than 200,000 U.S. prescriptions.



For more information on how to order canadian drugs safely and securely call 1-866-732-0305 or visit http://www.doctorsolve.com/ - a trusted and reliable Canada pharmacy for over 6 years.

Labels: baraclude, canadian drugs, chronic, damage, drugs, hepatitis B, infection, liver, medication, medicine, prescription drugs

It's no secret that proper diet - one rich in whole foods that
deliver essential vitamins and minerals - has been shown to
battle everything from cancer to the common cold. And for those
eager to achieve and maintain good health, a balanced,
nutritious diet is just part of the equation. But - as many may
not realize - diet also plays a significant role in the aging
process. Subsequently, a comprehensive and consistent antiaging
diet can allow you to live a longer, much healthier life.

Life expectancy has certainly increased throughout the
centuries, due in part to advances in medicine and technology.
But, as researchers learn more and more about the effects of
certain foods on the body, we, as consumers, have followed suit
- integrating healthier choices into our lives while minimizing
or even eliminating less healthy foods. An antiaging diet makes
use of the best in the foods available to use while avoiding
those foods that work against the natural processes of our
bodies.

The human body relies on billions and billions of tiny cells
that work together to perform all the functions we take for
granted. Cells - like stars in the sky - die; and in their
place new cells are formed. We have a direct impact on the
health of these new cells. Cells that are exposed to poor diet,
chemicals, environmental pollutants, and so forth, are
compromised and tend to be weaker than their previous
counterparts. These unhealthy cells can easily fall victim to
free radicals - unstable molecules in the body - and,
consequently a host of diseases.

But if we empower these cells with an antiaging diet that
includes proper nutrition they will have the tools necessary to
keep themselves healthy and working at optimum levels.

An antiaging diet is largely based on common sense. First and
foremost, increase your intake of fresh fruits and vegetables.
Concentrate on green, leafy vegetables or those with deep color
to them - spinach, kale, carrots - and eat a variety of all
different types. Specific vegetables contain high levels of
antioxidants. And all vegetables have a variety of vitamins and
minerals to keep your body healthy. There are those fruits that
contain antioxidants as well - apricots, watermelon, and
berries - and fruits of all varieties contain nutrients found
to fight heart disease and a myriad of illnesses.

Here are some good food sources of the four most studied antioxidants:

• Vitamin C -- Also called ascorbic acid, vitamin C is a water-soluble vitamin found in all body fluids, so it may be one of our first lines of defense. This powerful antioxidant cannot be stored by the body, so it's important to get some regularly -- not a difficult task if you eat fruits and vegetables. Important sources include citrus fruits, green peppers, broccoli, green leafy vegetables, strawberries, raw cabbage and potatoes.



• Vitamin E -- A fat-soluble vitamin that can be stored with fat in the liver and other tissues, vitamin E is promoted for a range of purposes -- from delaying aging to healing sunburn. While it's not a miracle worker, it's another powerful antioxidant. Important sources include wheat germ, nuts, seeds, whole grains, green leafy vegetables, vegetable oil and fish-liver oil.



• Beta-carotene -- The most studied of more than 600 different carotenoids that have been discovered, beta-carotene protects dark green, yellow and orange vegetables and fruits from solar radiation damage. It is thought that it plays a similar role in the body. Carrots, squash, broccoli, sweet potatoes, tomatoes, kale, collards, cantaloupe, peaches and apricots are particularly rich sources of beta-carotene.



• Selenium -- This mineral is thought to help fight cell damage by oxygen-derived compounds and thus may help protect against cancer. It is best to get selenium through foods, as large doses of the supplement form can be toxic. Good food sources include fish, shellfish, red meat, grains, eggs, chicken and garlic. Vegetables can also be a good source if grown in selenium-rich soils.

Eating a well-rounded antiaging diet rich in whole foods,
fruits, vegetables, complex carbohydrates, and protein - such
as lean meats and raw nuts - will ensure that you have all that
you need. But ensuring that you avoid what you don't need is
just as important. Minimize your intake of fatty, greasy, and
fried foods.

Just a little bit of effort on your part, your antiaging diet
will find you looking and feeling better and will put you well
on your way to enjoying a long and healthy life.

For easy to understand, in depth information
about antiaging visit the ezGuide 2
http://antiaging.ezguide2.com.

DoctorSolve Healthcare Solutions Inc., a Canadian Internet-based pharmacy intermediary (license #BC Q37),offers lower cost, long-term prescription drugs. A professionally registered pharmacist fills all prescriptions. A certified member of the Canadian International Pharmacy Association, DoctorSolve is ranked as one of the best Canadian pharmacies online by PharmacyChecker.com. DoctorSolve has filled more than 200,000 U.S. prescriptions.

For more information on how to order canadian drugs safely and securely call 1-866-732-0305 or visit http://www.doctorsolve.com/ - a trusted and reliable Canada pharmacy for over 6 years.

Findings from A Diabetes Outcome Progression Trial (ADOPT) study were met with both excitement and caution following a presentation at the International Diabetes Federation's World Diabetes Congress in Cape Town in early December.

The study was designed to compare the ability of rosiglitazone (Avandia), metformin and glyburide monotherapy to maintain long-term glycemic control in 4,360 recently diagnosed type II diabetes patients. The results showed that failure was 15% with rosiglitazone, 21% with metformin and 34% with glyburide - a 32% risk reduction for rosiglitazone compared with metformin and 63% compared with glyburide.

The positive findings, however, were tempered with some adverse events. Rosiglitazone was associated with a larger rate of weight gain and fluid retention when compared with the other two drugs. Close to 7% of patients in the rosiglitazone group experienced weight gain compared with only 1.2% of patients in the metformin group and 3.3% in the glyburide group. When 14% of patients in the rosiglitazone group suffered from edema only 7.2% in the metformin group and 8.5% in the glyburide group suffered.

Dr. Bernard Zinman, a member of the ADOPT steering committee and director of the diabetes centre at Mount Sinai Hospital in Toronto, said weight gain is an expected side-effect of rosiglitazone and that those evaluating the results should balance the positives with the negatives.

Dr. Zinman also pointed out that the overall number of deaths was low in all three groups, and rosiglitazone and metformin performed similarly well with respect to myocardial infarction and congestive heart failure.

In both test groups, 0.1% of patients suffered a fatal MI and 0.8% had congestive heart failure. "These are negative attributes to rosiglitazone, like there are negative attributes to metformin and glyburide," Dr. Zinman said.

"We now have good evidence that in a population of recent onset type II diabetes...rosiglitazone clearly provides a more durable glycemic effect."

Agreeing with Dr.Zinman, Dr. Ian Blumer, a councillor of the Canadian Diabetes Association's clinical and scientific section and an internist in Ajax, Ont., stated the overall effects were positive, but weight gain was definitely still a concern.

Because many type 2 diabetics are overweight and advised to keep their weight under control, Dr. Blumer said a drug that works against those efforts might be disheartening. "I don't think we can minimize the impact of that in terms of the health outcomes and the psychological outcomes," he said.

"I am pleased the study was positive, but the question in my mind is, was the study positive enough that I can ignore or downplay the impact of the weight gain and say ... we should be prescribing (rosiglitazone) in practice? I'm not sure about that yet."

Both doctors agreed that due to the nature of type II diabetes and these drugs, many patients may eventually be prescribed both metformin and rosiglitazone, sometimes in combination.

"I'm of the opinion that we probably should be using combination therapies early, and not necessarily going to maximum dose of one agent before we go to the next," Dr. Zinman said. "I like the notion of using two agents at submaximal doses so you don't get the big side-effects but you get the complmentary effects on lowering glucose."

DoctorSolve Healthcare Solutions Inc., a Canadian Internet-based pharmacy intermediary (license #BC Q37),offers lower cost, long-term prescription drugs. A professionally registered pharmacist fills all prescriptions. A certified member of the Canadian International Pharmacy Association, DoctorSolve is ranked as one of the best Canadian pharmacies online by PharmacyChecker.com. DoctorSolve has filled more than 200,000 U.S. prescriptions.

For more information on how to order canadian drugs safely and securely call 1-866-732-0305 or visit http://www.doctorsolve.com/ - a trusted and reliable Canada pharmacy for over 6 years.

How does Pyralvex work?

Pyralvex solution contains two active ingredients, salicyclic acid and rhubarb extract.

Salicylic acid is a type of medicine called a salicylate. It works by blocking the action of a substance in the body called cyclo-oxygenase. Cyclo-oxygenase is involved in the production of various chemicals in the body, including some known as prostaglandins. Prostaglandins have many actions, and are involved in causing inflammation. The body produces prostaglandins in response to injury and they cause an increase in the blood supply to the area of damage. This results in swelling, heat, redness and pain in that area.

By blocking cyclo-oxygenase, salicylic acid stops the formation of prostaglandins and therefore reduces inflammation and pain in the area of the mouth it is applied to.

The rhubarb extract contains anthraquinone glycosides, which also help to relieve inflammation.

What is it used for?

Pyralvex solution is used to relieve the pain and discomfort caused by mouth ulcers and denture irritation. The solution also has some antimicrobial properties that help prevent the irritated areas from getting infected.

The solution should be applied to the sore area of the mouth three to four times daily using the brush provided. Avoid rinsing the mouth or eating for 15 minutes after use of Pyralvex.

For denture irritation, leave 30 minutes after applying the solution before putting the dentures back in. Don't apply Pyralvex solution directly to the dentures, as this can further irritate the gums.

What important information should I know about Pyralvex?

• Each bottle of this medicine should only be used by one person.
  
• Do not exceed the recommended dose.
  
• Avoid rinsing the mouth or eating for 15 minutes after using Pyralvex.
  
• When applied for denture irritation, leave 30 minutes after applying the gel before putting the dentures back in. Don't apply the gel directly to the dentures, as this can further irritate the gums.
  
• Pyralvex is a coloured liquid and can stain material. Care should be taken to ensure that the liquid is not spilt or dropped onto clothing.
  
• There are no known harmful effects when this medicine is used by pregnant or breastfeeding mothers.
  
• Pyralvex can not be used in children under the age of 12.
  
• This medicine is not known to interact with other medicines.
  

Does Pyralvex have any side effects?

Pyralvex and it's possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine:

• Ulceration at site of application if used excessively.
  
• Pyralvex may cause some discolouration of the mouth or teeth, but this will be removed with normal teeth brushing.

DoctorSolve Healthcare Solutions Inc., a Canadian Internet-based pharmacy intermediary (license #BC Q37),offers lower cost, long-term prescription drugs. A professionally registered pharmacist fills all prescriptions. A certified member of the Canadian International Pharmacy Association, DoctorSolve is ranked as one of the best Canadian pharmacies online by PharmacyChecker.com. DoctorSolve has filled more than 200,000 U.S. prescriptions.

For more information on how to order canadian drugs safely and securely call 1-866-732-0305 or visit http://www.doctorsolve.com/ - a trusted and reliable Canada pharmacy for over 6 years.